ADReCS

Pharmaceutical Information

Drug Name	Isoniazid
Drug ID	BADD_D01204
Description	Antibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.
Indications and Usage	For the treatment of all forms of tuberculosis in which organisms are susceptible.
Marketing Status	approved; investigational
ATC Code	J04AC01
DrugBank ID	DB00951
KEGG ID	D00346
MeSH ID	D007538
PubChem ID	3767
TTD Drug ID	D09XQF
NDC Product Code	60687-553; 0555-0071; 71610-395; 83112-071; 50090-0410; 63187-978; 0555-0066; 68788-9405; 71610-108; 12785-0003; 50090-0370; 70518-0096; 70518-2576; 43063-463; 62135-550; 0781-3056; 12785-0002; 66639-914; 51079-083; 43367-0100; 71052-611; 46287-009; 71335-0275; 53002-2920
UNII	V83O1VOZ8L
Synonyms	Isoniazid \| Isonicotinic Acid Hydrazide \| Hydrazide, Isonicotinic Acid \| Phthivazide \| Phthivazid \| Isonicotinic Acid Vanillylidenehydrazide \| Acid Vanillylidenehydrazide, Isonicotinic \| Vanillylidenehydrazide, Isonicotinic Acid \| Ftivazide \| Tubazide \| Isonex

Chemical Information

Molecular Formula	C6H7N3O
CAS Registry Number	54-85-3
SMILES	C1=CN=CC=C1C(=O)NN
Chemical Structure

ADRs Induced by Drug

*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..

ADR Term	ADReCS ID	ADR Frequency (FAERS)	ADR Severity Grade (FAERS)	ADR Severity Grade (CTCAE)
Pancytopenia	01.03.03.003	0.006949%		Not Available
Paraesthesia	23.03.03.094; 17.02.06.005	-	-
Paralysis	17.01.04.004	0.005560%		Not Available
Pemphigoid	23.03.01.004; 10.04.02.002	0.002780%		Not Available
Pericardial effusion	02.06.01.002	0.009729%
Periorbital oedema	23.04.01.002; 10.01.05.010; 06.08.03.017	-	-
Personality disorder	19.05.02.002	-	-	Not Available
Petechiae	23.06.01.003; 01.01.03.002; 24.07.06.004	0.002780%		Not Available
Pleural effusion	22.05.02.002	0.008339%
Pneumonitis	22.01.01.006	0.008339%
Pneumothorax	22.05.02.003	0.002780%
Polyuria	20.02.03.002	-	-	Not Available
Premature baby	18.04.02.001	0.005560%		Not Available
Premature delivery	18.07.01.006	0.007505%
Presyncope	24.06.02.010; 02.11.04.013; 17.02.05.009	0.002780%
Proteinuria	20.02.01.011	0.008339%
Pruritus	23.03.12.001	-	-
Pulmonary alveolar haemorrhage	22.01.02.005; 24.07.01.015	0.004170%		Not Available
Pulmonary fibrosis	22.01.02.006	0.004170%
Pulmonary oedema	22.01.03.003; 02.05.02.003	0.005560%
Purpura	24.07.06.005; 23.06.01.004; 01.01.04.003	-	-
Pyrexia	08.05.02.003	0.048646%
Rash	23.03.13.001	-	-	Not Available
Rash erythematous	23.03.13.029	0.006949%		Not Available
Rash macular	23.03.13.003	0.004170%		Not Available
Rash maculo-papular	23.03.13.004	0.017234%
Rash pruritic	23.03.13.030	0.004170%		Not Available
Renal disorder	20.01.02.002	0.002780%		Not Available
Renal failure	20.01.03.005	0.008339%		Not Available
Respiratory acidosis	22.02.02.004; 14.01.04.002	0.002780%		Not Available

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