Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Halobetasol
Drug ID BADD_D01051
Description Ulobetasol is a highly potent corticosteroid.[A215597] It is structurally related to [clobetasol].[A215597] Due to its high potency, it is mainly prescribed in the treatment of severe plaque psoriasis and corticosteroid responsive dermatoses.[L15047,L15052,L15102] Ulobetasol was granted FDA approval on 17 December 1990.[L15047]
Indications and Usage Ulobetasol cream and ointment are indicated in the treatment of inflammatory and pruritic corticosteroid responsive dermatoses.[L15047] Ulobetasol lotion is indicated in the treatment of plaque psoriasis.[L15052]
Marketing Status approved
ATC Code D07AC21
DrugBank ID DB00596
KEGG ID D08660
MeSH ID C064466
PubChem ID 5311167
TTD Drug ID D00XPC
NDC Product Code Not Available
UNII 9P6159HM7T
Synonyms halobetasol | ulobetasol | Ultravate | halobetasol propionate | 6 alpha-fluoroclobetasol 17-propionate | 6-fluoroclobetasol 17-propionate | CGP 14 458 | CGP-14458 | CGP 14458
Chemical Information
Molecular Formula C22H27ClF2O4
CAS Registry Number 98651-66-2
SMILES CC1CC2C3CC(C4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CCl)O)C)O)F)C)F
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Folliculitis23.11.04.003; 11.02.01.053--
Generalised tonic-clonic seizure17.12.01.002--Not Available
Gynaecomastia21.05.04.003; 05.05.02.003--
Hallucination19.10.04.003--
Headache17.14.01.001--
Heat stroke24.06.02.009; 12.05.01.001--Not Available
Hepatic function abnormal09.01.02.001--Not Available
Hyperammonaemia14.10.01.001; 09.01.02.002--Not Available
Hyperglycaemia14.06.02.002; 05.06.02.002--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hyperpyrexia08.05.02.002--Not Available
Hypertension24.08.02.001--
Hypertrichosis23.02.04.002--
Hypoglycaemia14.06.03.001; 05.06.03.001--
Hyponatraemia14.05.04.002--
Hypotension24.06.03.002--
Infection11.01.08.002--Not Available
Insomnia17.15.03.002; 19.02.01.002--
Jaundice23.03.03.030; 09.01.01.004; 01.06.04.004--Not Available
Laryngospasm22.04.02.002--
Lethargy08.01.01.008; 19.04.04.004; 17.02.04.003--
Leukocytosis01.02.01.002--
Leukoderma23.05.02.001--Not Available
Leukopenia01.02.02.001--Not Available
Libido increased21.03.02.007; 19.08.03.002--
Menstruation irregular05.05.01.008; 21.01.01.005--
Miliaria23.02.03.014--Not Available
Monocytosis01.02.01.004--Not Available
Nausea07.01.07.001--
Neuroleptic malignant syndrome17.05.02.003; 12.03.01.003; 15.05.04.015; 08.05.01.005--Not Available
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