Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Glatiramer acetate
Drug ID BADD_D01021
Description Glatiramer acetate consists of the acetate salts of synthetic polypeptides, containing four naturally occurring amino acids: L-glutamic acid, L-alanine, L-tyrosine, and L-lysine with an average molar fraction of 0.141, 0.427, 0.095, and 0.338, respectively. The average molecular weight of glatiramer acetate is 5,000-9,000 daltons. It is an immunomodulator, licensed in much of the world for reduced frequency of relapses in relapsing-remitting multiple sclerosis.
Indications and Usage For reduction of the frequency of relapses in patients with Relapsing-Remitting Multiple Sclerosis.
Marketing Status Prescription; Discontinued
ATC Code L03AX13
DrugBank ID DB05259
KEGG ID D04318
MeSH ID D000068717
PubChem ID 3081884
TTD Drug ID D04CRL
NDC Product Code 0441-3642; 0378-6960; 63629-8815; 68546-317; 63629-8816; 65129-1181; 63850-4035; 55111-945; 24795-0063; 0781-3250; 59651-517; 53104-7715; 14403-0008; 0781-3234; 24795-0068; 68546-325
Synonyms Glatiramer Acetate | Acetate, Glatiramer | Copaxone | Glatiramer | TV 5010 | 5010, TV | TV5010 | TV-5010
Chemical Information
Molecular Formula C25H45N5O13
CAS Registry Number 147245-92-9
SMILES CC(C(=O)O)N.CC(=O)O.C1=CC(=CC=C1CC(C(=O)O)N)O.C(CCN)CC(C(=O)O)N.C(CC(=O)O)C(C(=O )O)N
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Osteomyelitis15.02.05.001; 11.01.01.001--
Otitis externa11.01.05.003; 04.01.02.001--
Ovarian cancer21.11.01.003; 16.12.04.001--Not Available
Ovarian cyst21.11.01.002; 16.04.03.001--Not Available
Pain08.01.08.004--
Palpitations02.01.02.003--
Pancreatic disorder07.18.02.001--Not Available
Pancreatitis07.18.01.001--
Pancytopenia01.03.03.003--Not Available
Paraesthesia17.02.06.005--
Paranoia19.05.01.005--Not Available
Paraplegia17.01.04.007--Not Available
Pericardial effusion02.06.01.002--
Peripheral vascular disorder24.03.01.003--Not Available
Peroneal nerve palsy17.09.02.003--Not Available
Pharyngitis22.07.03.004; 11.01.13.003; 07.05.07.004--
Photophobia06.01.01.004; 17.17.02.006--
Photosensitivity reaction23.03.09.003--
Pleural effusion22.05.02.002--
Pneumonia22.07.01.003; 11.01.09.003--Not Available
Pollakiuria20.02.02.007--
Priapism21.03.01.005--Not Available
Proctalgia07.03.02.001--
Pruritus23.03.12.001--
Pseudolymphoma01.09.01.016--Not Available
Psoriasis23.03.14.002; 10.02.01.036--Not Available
Pulmonary embolism24.01.06.001; 22.06.02.001--Not Available
Purpura23.06.01.004; 01.01.04.003; 24.07.06.005--
Pyelonephritis20.01.09.001; 11.01.14.002--Not Available
Pyrexia08.05.02.003--
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