Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Glatiramer
Drug ID BADD_D01020
Description Glatiramer acetate consists of the acetate salts of synthetic polypeptides, containing four naturally occurring amino acids: L-glutamic acid, L-alanine, L-tyrosine, and L-lysine with an average molar fraction of 0.141, 0.427, 0.095, and 0.338, respectively. The average molecular weight of glatiramer acetate is 5,000-9,000 daltons. It is an immunomodulator, licensed in much of the world for reduced frequency of relapses in relapsing-remitting multiple sclerosis.
Indications and Usage For reduction of the frequency of relapses in patients with Relapsing-Remitting Multiple Sclerosis.
Marketing Status Prescription; Discontinued
ATC Code L03AX13
DrugBank ID DB05259
KEGG ID D04318
MeSH ID D000068717
PubChem ID 65370
TTD Drug ID D04CRL
NDC Product Code 41524-0004; 0378-6961
Synonyms Glatiramer Acetate | Acetate, Glatiramer | Copaxone | Glatiramer | TV 5010 | 5010, TV | TV5010 | TV-5010
Chemical Information
Molecular Formula C23H41N5O11
CAS Registry Number 28704-27-0
SMILES CC(C(=O)O)N.C1=CC(=CC=C1CC(C(=O)O)N)O.C(CCN)CC(C(=O)O)N.C(CC(=O)O)C(C(=O)O)N
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Pain08.01.08.004--
Palpitations02.01.02.003--
Pancreatic disorder07.18.02.001--Not Available
Pancreatitis07.18.01.001--
Pancytopenia01.03.03.003--Not Available
Paranoia19.05.01.005--Not Available
Paraplegia17.01.04.007--Not Available
Pericardial effusion02.06.01.002--
Peripheral vascular disorder24.03.01.003--Not Available
Photophobia17.17.02.006; 06.01.01.004--
Photosensitivity reaction23.03.09.003--
Pleural effusion22.05.02.002--
Pneumonia22.07.01.003; 11.01.09.003--Not Available
Pollakiuria20.02.02.007--
Priapism21.03.01.005--Not Available
Proctalgia07.03.02.001--
Pruritus23.03.12.001--
Pseudolymphoma01.09.01.016--Not Available
Psoriasis10.02.01.036; 23.03.14.002--Not Available
Pulmonary embolism24.01.06.001; 22.06.02.001--Not Available
Pyelonephritis20.01.09.001; 11.01.14.002--Not Available
Rash23.03.13.001--Not Available
Rash maculo-papular23.03.13.004--
Rash pustular11.01.12.002; 23.03.10.003--
Rectal haemorrhage24.07.02.018; 07.12.03.001--
Renal failure20.01.03.005--Not Available
Renal pain20.02.03.003--Not Available
Respiratory failure22.02.06.002; 14.01.04.003--
Rheumatoid arthritis10.04.06.001; 15.01.03.001--Not Available
Rhinitis22.07.03.006; 11.01.13.004--
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