Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cytarabine hydrochloride
Drug ID BADD_D00561
Description A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p472)
Indications and Usage For the treatment of acute non-lymphocytic leukemia, acute lymphocytic leukemia and blast phase of chronic myelocytic leukemia.
Marketing Status Prescription; Discontinued
ATC Code L01BC01
DrugBank ID DB00987
KEGG ID D03637
MeSH ID D003561
PubChem ID 6252
TTD Drug ID D07XSN
NDC Product Code 12848-1003; 61703-303; 61703-319; 71288-108; 71288-168; 55512-0026; 67457-455; 68083-343; 71288-109; 61703-305; 71288-169; 58623-0026; 70516-0163; 61703-304; 63323-120; 67457-452; 68083-337
Synonyms Cytarabine | Arabinosylcytosine | Cytosine Arabinoside | Arabinoside, Cytosine | Arabinofuranosylcytosine | Aracytidine | beta-Ara C | beta Ara C | Cytarabine Hydrochloride | Cytosar | Cytosar-U | Cytosar U | Ara-C | Ara C | Aracytine | Cytonal
Chemical Information
Molecular Formula C9H13N3O5.ClH
CAS Registry Number 69-74-9
SMILES C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)O.Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Haemoglobin13.01.05.018--Not Available
Haemorrhoids24.10.02.002; 07.15.03.001--
Headache17.14.01.001--
Hemiplegia17.01.04.002--Not Available
Hepatic function abnormal09.01.02.001--Not Available
Hepatocellular injury09.01.07.008--Not Available
Hydrocephalus17.07.01.001--
Hyperbilirubinaemia14.11.01.010; 09.01.01.003; 01.06.04.003--Not Available
Hyperglycaemia14.06.02.002; 05.06.02.002--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
Hyperuricaemia14.09.01.003--
Hypoaesthesia17.02.06.023--Not Available
Hypocalcaemia14.04.01.004--
Hypokalaemia14.05.03.002--
Hyponatraemia14.05.04.002--
Hypotension24.06.03.002--
Hypoxia22.02.02.003--
Ileus07.13.01.001--
Immune system disorder10.02.01.001--Not Available
Incontinence20.02.02.004; 17.05.01.006; 07.01.06.011--Not Available
Infection11.01.08.002--Not Available
Injection site reaction08.02.03.014; 12.07.03.015--
Insomnia19.02.01.002; 17.15.03.002--
Interstitial lung disease10.02.01.033; 22.01.02.003--Not Available
Jaundice23.03.03.030; 09.01.01.004; 01.06.04.004--Not Available
Keratitis06.04.02.002--
Lacrimation increased06.08.02.004--
Lethargy19.04.04.004; 17.02.04.003; 08.01.01.008--
The 3th Page    First    Pre   3 4 5 6 7    Next   Last    Total 8 Pages