Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Brain abscess
ADR ID BADD_A00663
ADR Hierarchy
11      Infections and infestations
11.01      Infections - pathogen unspecified
11.01.03      Central nervous system and spinal infections
11.01.03.003      Brain abscess
17      Nervous system disorders
17.06      Central nervous system infections and inflammations
17.06.07      Central nervous system abscesses
17.06.07.001      Brain abscess
Description A circumscribed collection of purulent exudate in the brain, due to bacterial and other infections. The majority are caused by spread of infected material from a focus of suppuration elsewhere in the body, notably the PARANASAL SINUSES, middle ear (see EAR, MIDDLE); HEART (see also ENDOCARDITIS, BACTERIAL), and LUNG. Penetrating CRANIOCEREBRAL TRAUMA and NEUROSURGICAL PROCEDURES may also be associated with this condition. Clinical manifestations include HEADACHE; SEIZURES; focal neurologic deficits; and alterations of consciousness. (Adams et al., Principles of Neurology, 6th ed, pp712-6) [MeSH]
MedDRA Code 10006105
MeSH ID D001922; D001922; D001922
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Brain abscess | Brain abscess NOS | Intracranial abscess | Cerebral abscess | Brain Abscess | Abscess, Brain | Brain Abscesses | Brain Abscess, Child | Abscess, Child Brain | Child Brain Abscess | Brain Abscess, Sterile | Brain Abscesses, Sterile | Sterile Brain Abscess | Sterile Brain Abscesses | Cerebral Abscess | Abscess, Cerebral | Abscesses, Cerebral | Cerebral Abscesses | Brain Abscess, Multiple | Abscess, Multiple Brain | Abscesses, Multiple Brain | Brain Abscesses, Multiple | Multiple Brain Abscess | Multiple Brain Abscesses | Brain Abscess, Pyogenic | Abscess, Pyogenic Brain | Brain Abscesses, Pyogenic | Pyogenic Brain Abscess | Pyogenic Brain Abscesses
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00129Amoxicillin0.000005%
BADD_D00195Azathioprine0.001436%
BADD_D00284Bortezomib0.000533%
BADD_D00285Bosentan0.000117%
BADD_D00349Capecitabine0.000139%
BADD_D00371Carmustine0.001332%
BADD_D00475Citalopram0.000022%
BADD_D00497Clomiphene--
BADD_D00498Clomiphene citrate--
BADD_D00511Clozapine0.016814%
BADD_D00551Cyclosporine0.000135%
BADD_D00623Dexamethasone0.000537%
BADD_D00680Dimethyl fumarate0.001834%
BADD_D01119Ibrutinib0.001332%
BADD_D01253Lenalidomide--
BADD_D01254Lenvatinib0.000533%
BADD_D01507Mycophenolate mofetil0.000853%
BADD_D01834Prednisone0.000219%
BADD_D01933Ribavirin0.027196%
BADD_D01978Ruxolitinib0.000533%
BADD_D02105Tacrolimus0.002129%
BADD_D02236Tofacitinib0.001737%
BADD_D02268Treprostinil0.000371%
BADD_D02369Voriconazole0.053245%
BADD_D02392Zoledronic acid0.006846%
BADD_D02464Fingolimod0.002316%
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