Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Benign hydatidiform mole
ADR ID BADD_A00436
ADR Hierarchy
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.04      Reproductive neoplasms female benign
16.04.01      Reproductive neoplasms female benign NEC
16.04.01.002      Benign hydatidiform mole
18      Pregnancy, puerperium and perinatal conditions
18.05      Placental, amniotic and cavity disorders (excl haemorrhages)
18.05.03      Placental neoplasms
18.05.03.001      Benign hydatidiform mole
21      Reproductive system and breast disorders
21.07      Uterine, pelvic and broad ligament disorders
21.07.02      Uterine neoplasms
21.07.02.006      Benign hydatidiform mole
Description Trophoblastic hyperplasia associated with normal gestation, or molar pregnancy. It is characterized by the swelling of the CHORIONIC VILLI and elevated human CHORIONIC GONADOTROPIN. Hydatidiform moles or molar pregnancy may be categorized as complete or partial based on their gross morphology, histopathology, and karyotype. | Derived from the fertilization of an anuclear ovum by one or sometimes two haploid sperm. Its molar chromosomes derive entirely from the paternal origin. It has no identifiable embryonic or fetal tissue. The chorionic villi have generalized swelling and diffuse trophoblastic hyperplasia. Most complete moles (>90%) have a 46,XX karyotype and the rest 46,XY karyotype. | Derived from the fertilization of an apparently normal ovum by two sperm. Partial hydatidiform moles are characterized by focal chorionic villi swelling, focal trophoblastic hyperplasia, and identifiable fetal or embryonic tissue. Partial moles generally have a triploid karyotype. [MeSH]
MedDRA Code 10004272
MeSH ID D006828
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Benign hydatidiform mole | Hydatidiform mole | Hydatidiform mole benign | Hydatidiform mole NOS | Molar pregnancy | Hydatidiform Mole | Hydatidiform Moles | Mole, Hydatidiform | Moles, Hydatidiform | Pregnancy, Molar | Molar Pregnancy | Molar Pregnancies | Pregnancies, Molar | Hydatid Mole | Hydatid Moles | Mole, Hydatid | Moles, Hydatid | Hydatidiform Mole, Complete | Complete Hydatidiform Mole | Complete Hydatidiform Moles | Hydatidiform Moles, Complete | Mole, Complete Hydatidiform | Moles, Complete Hydatidiform | Hydatidiform Mole, Partial | Hydatidiform Moles, Partial | Mole, Partial Hydatidiform | Moles, Partial Hydatidiform | Partial Hydatidiform Mole | Partial Hydatidiform Moles
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00498Clomiphene citrate--
BADD_D00680Dimethyl fumarate0.001834%
BADD_D01103Hydroxychloroquine0.000405%
BADD_D01281Levonorgestrel0.010423%
BADD_D01366Medroxyprogesterone acetate--
BADD_D01401Metformin0.000026%
BADD_D02319Urofollitropin--
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