Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Coarctation of the aorta
ADR ID BADD_A00964
ADR Hierarchy
03      Congenital, familial and genetic disorders
03.07      Cardiac and vascular disorders congenital
03.07.08      Great vessel disorders congenital
03.07.08.001      Coarctation of the aorta
24      Vascular disorders
24.04      Arteriosclerosis, stenosis, vascular insufficiency and necrosis
24.04.01      Aortic necrosis and vascular insufficiency
24.04.01.002      Coarctation of the aorta
Description A birth defect characterized by the narrowing of the AORTA that can be of varying degree and at any point from the transverse arch to the iliac bifurcation. Aortic coarctation causes arterial HYPERTENSION before the point of narrowing and arterial HYPOTENSION beyond the narrowed portion. [MeSH]
MedDRA Code 10009807
MeSH ID D001017; D001017; D001017
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Aortic coarctation | Coarctation of aorta | Coarctation of aorta (preductal) (postductal) | Coarctation of the aorta | Aortic Coarctation | Aortic Coarctations | Coarctation, Aortic | Coarctations, Aortic | Coarctation of the Aorta | Coarctation of Aorta | Aorta Coarctation | Aorta Coarctations | Coarctation of Aorta Dominant | Aorta Dominant Coarctation | Aorta Dominant Coarctations
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00312Bupropion0.000046%
BADD_D00475Citalopram0.000033%
BADD_D00497Clomiphene--
BADD_D00498Clomiphene citrate--
BADD_D00809Escitalopram0.000161%
BADD_D00932Fluoxetine0.000284%
BADD_D01243Lamotrigine0.000370%
BADD_D01265Levetiracetam0.000447%
BADD_D01401Metformin0.000020%
BADD_D01617Ondansetron0.000130%
BADD_D01679Paroxetine0.000683%
BADD_D02010Sertraline0.000142%
BADD_D02047Sodium oxybate0.000316%
BADD_D02053Sofosbuvir0.001447%
BADD_D02247Topiramate0.000062%
BADD_D02329Valproic acid0.000289%
BADD_D02346Venlafaxine0.000039%
BADD_D02464Fingolimod--
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