Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Clomiphene
Drug ID BADD_D00497
Description A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue.
Indications and Usage Used mainly in female infertility due to anovulation (e.g. due to polycystic ovary syndrome) to induce ovulation.
Marketing Status Prescription; Discontinued
ATC Code G03GB02
DrugBank ID DB00882
KEGG ID D07726
MeSH ID D002996
PubChem ID 1548953
TTD Drug ID D0CT9Y
NDC Product Code Not Available
Synonyms Clomiphene | Clomifene | Chloramiphene | Clomifen | Clomiphene Citrate | Citrate, Clomiphene | Clomiphene Hydrochloride | Hydrochloride, Clomiphene | Serophene | Gravosan | Klostilbegit | Clostilbegit | Clomid | Clomide | Dyneric
Chemical Information
Molecular Formula C26H28ClNO
CAS Registry Number 15690-57-0
SMILES CCN(CC)CCOC1=CC=C(C=C1)C(=C(C2=CC=CC=C2)Cl)C3=CC=CC=C3
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Eye pain06.08.03.002--
Fallot's tetralogy03.07.06.001; 02.08.01.002--Not Available
Fatigue08.01.01.002--
Fibrocystic breast disease21.05.01.002; 16.14.01.003--Not Available
Flatulence07.01.04.002--
Flushing23.06.05.003; 08.01.03.025; 24.03.01.002--
Glioblastoma multiforme17.20.02.001; 16.30.02.001--Not Available
Haemangioma24.03.06.004; 16.02.01.002--Not Available
Hair texture abnormal23.02.06.004--
Headache17.14.01.001--
Heart disease congenital02.01.01.009; 03.07.07.001--Not Available
Hepatic adenoma16.06.01.002; 09.04.01.002--Not Available
Hepatitis09.01.07.004--Not Available
Hepatocellular injury09.01.07.008--Not Available
Hodgkin's disease16.31.01.001; 01.16.01.001--Not Available
Hodgkin's disease lymphocyte depletion type stage unspecified01.16.03.001; 16.31.03.001--Not Available
Hodgkin's disease lymphocyte predominance type stage unspecified01.16.04.001; 16.31.04.001--Not Available
Hydrocephalus17.07.01.001--
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
Hypertrichosis23.02.04.002--
Hypertriglyceridaemia14.08.02.001--
Hypovolaemia14.05.05.002--Not Available
Ichthyosis03.05.01.004; 23.01.02.002--Not Available
Ichthyosis acquired23.01.02.001--Not Available
Increased appetite14.03.01.003; 08.01.09.027--Not Available
Inguinal hernia07.16.02.001--Not Available
Insomnia19.02.01.002; 17.15.03.002--
Irritability08.01.03.011; 19.04.02.013--
Jaundice23.03.03.030; 09.01.01.004; 01.06.04.004--Not Available
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