Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cefprozil
Drug ID BADD_D00397
Description Cefprozil is a cephalosporin antibiotic that is commonly employed to treat a variety of bacterial infections, including those of the ear and skin, bronchitis, and others.
Indications and Usage For the treatment of the following infections (respiratory, skin, soft tissue, UTI, ENT) caused by; S. pneumoniae, H. influenzae, staphylococci, S. pyogenes (group A beta-hemolytic streptococci), E. coli, P. mirabilis, Klebsiella sp, coagulase-negative staph
Marketing Status Prescription; Discontinued
ATC Code J01DC10
DrugBank ID DB01150
KEGG ID D00261
MeSH ID C052018
PubChem ID 5281006
TTD Drug ID D0YX4S
NDC Product Code 68180-401; 16714-399; 16714-398; 68180-402; 61788-4000; 0093-1077; 16714-396; 65862-069; 65862-068; 57297-400; 16714-397; 67296-1180; 68180-404; 68180-403; 65862-099; 50090-1188; 65862-100; 57237-037; 57237-035; 50090-1739; 57237-036; 57237-034; 50090-1710; 65862-378; 0093-1078
Synonyms cefprozil | BMY 28100 | BMY-28100 | 7-(2-amino-2-(p-hydroxyphenyl)acetamido)-8-oxo-3-(1-propenyl)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid | cefprozil monohydrate | 7-(2-amino-2-(4-hydroxyphenyl)acetamido)-3-(propenyl)-3-cephem-4-carboxylic acid monohydrate | Cefzil | Procef | Arzimol | Brisoral
Chemical Information
Molecular Formula C18H19N3O5S
CAS Registry Number 92676-86-3
SMILES CC=CC1=C(N2C(C(C2=O)NC(=O)C(C3=CC=C(C=C3)O)N)SC1)C(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Headache17.14.01.001--
Hyperkinesia17.01.02.008--Not Available
Hypersensitivity10.01.03.003--
Insomnia19.02.01.002; 17.15.03.002--
Jaundice cholestatic09.01.01.005--Not Available
Nausea07.01.07.001--
Nephropathy toxic12.03.01.010; 20.05.03.002--Not Available
Nervousness19.06.02.003--Not Available
Neutropenia01.02.03.004--Not Available
Pain08.01.08.004--
Pancytopenia01.03.03.003--Not Available
Pharyngitis22.07.03.004; 11.01.13.003; 07.05.07.004--
Pneumonia streptococcal22.07.06.006; 11.02.06.005--Not Available
Prothrombin level increased13.01.02.011--Not Available
Pruritus23.03.12.001--
Pruritus genital21.10.01.002; 23.03.12.008--Not Available
Pseudomembranous colitis11.02.02.002; 07.19.01.003--Not Available
Psychomotor hyperactivity19.11.02.003; 17.01.02.011--Not Available
Rash23.03.13.001--Not Available
Seizure17.12.03.001--
Serum sickness12.02.08.004; 10.01.03.004--
Somnolence19.02.05.003; 17.02.04.006--
Stevens-Johnson syndrome11.07.01.005; 10.01.03.020; 23.03.01.007; 12.03.01.014--
Superinfection11.01.08.009--Not Available
Tension19.06.02.005--Not Available
Thrombocytopenia01.08.01.002--Not Available
Tonsillitis22.07.03.008; 11.01.13.006--Not Available
Tooth discolouration07.09.02.001--
Toxic epidermal necrolysis23.03.01.008; 12.03.01.015; 11.07.01.006; 10.01.01.006--
Urticaria23.04.02.001; 10.01.06.001--
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