Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cefdinir
Drug ID BADD_D00384
Description Cefdinir, also known as Omnicef, is a semi-synthetic, broad-spectrum antibiotic belonging to the third generation of the cephalosporin class. It has been proven to be effective for the treatment of common bacterial infections in the ear, sinus, throat, lungs, and skin. Cefdinir was approved by the FDA in 1997 to treat a variety of mild to moderate infections and was initially marketed by Abbvie.[A180739] Because of its chemical structure, it is effective against organisms that are resistant to first-line cephalosporin therapy due to the production of beta-lactamase enzymes.[A180724,A180727]
Indications and Usage For the treatment of the respiratory, skin, soft tissue, and ENT infections caused by H. influenzae (including b-lactamase producing strains), H. parainfluenzae (including b-lactamase producing strains), S. pneumoniae (penicillin-susceptible strains), S. pyogenes, S. aureus (including b-lactamase producing strains), and M. catarrhalis.
Marketing Status Prescription; Discontinued
ATC Code J01DD15
DrugBank ID DB00535
KEGG ID D00917
MeSH ID D000077525
PubChem ID 6915944
TTD Drug ID D0WS1X
NDC Product Code 70518-2537; 71205-576; 67296-1216; 72189-043; 72189-308; 68180-711; 67877-547; 67296-0765; 67296-0469; 68071-5145; 50090-1031; 67877-548; 0781-6078; 68071-2564; 50090-3724; 63629-8969; 68788-7478; 0093-4136; 71205-380; 71205-224; 68180-722; 65862-384; 50090-2719; 61788-2000; 68001-362; 68788-7844; 68071-1788; 65862-177; 68071-4946; 72189-186; 70934-164; 71205-405; 68071-4792; 68071-3295; 63187-835; 63187-616; 72789-054; 72189-042; 16714-393; 68071-4419; 68788-8115; 50090-1029; 67877-543; 68788-7987; 72189-185; 72789-061; 68071-2599; 63187-989; 50090-1034; 0093-3160; 68071-2493; 50090-1027; 68071-1645; 43063-964; 68788-7339; 68071-2503; 61919-840; 68071-2401; 0093-4137; 71205-183; 70934-343; 68071-5106; 16714-392; 65862-219; 50090-5583; 68180-723; 68071-4856; 0781-6077; 50090-5811; 68071-4007; 53002-1526; 50090-1033; 67296-0868; 65862-218; 0781-2176; 16714-391; 50090-3723; 72189-259; 70934-062; 50090-2735; 57237-099; 68071-4970; 68788-8062; 43063-959; 70934-044
Synonyms Cefdinir | FK 482 | FK-482 | FK482 | PD 134393 | PD-134393 | 7-(2 (2-Aminothiazol-4-yl)-2-hydroxyiminoacetamido)-3-vinyl-3-cephem-4-carboxylic acid | CI 983 | CI-983 | CI983 | Omnicef
Chemical Information
Molecular Formula C14H13N5O5S2
CAS Registry Number 91832-40-5
SMILES C=CC1=C(N2C(C(C2=O)NC(=O)C(=NO)C3=CSC(=N3)N)SC1)C(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Jaundice09.01.01.004; 23.03.03.030; 01.06.04.004--Not Available
Laryngeal oedema10.01.05.003; 23.04.01.005; 22.04.02.001--
Leukopenia01.02.02.001--Not Available
Loss of consciousness17.02.04.004--Not Available
Melaena24.07.02.013; 07.12.02.004--Not Available
Myocardial infarction24.04.04.009; 02.02.02.007--
Nausea07.01.07.001--
Nephropathy20.05.03.001--Not Available
Nephropathy toxic20.05.03.002; 12.03.01.010--Not Available
Neutropenia01.02.03.004--Not Available
Pancytopenia01.03.03.003--Not Available
Peptic ulcer07.04.07.001--Not Available
Pneumonia11.01.09.003; 22.07.01.003--Not Available
Pruritus23.03.12.001--
Pseudomembranous colitis11.02.02.002; 07.19.01.003--Not Available
Purpura24.07.06.005; 23.06.01.004; 01.01.04.003--
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Rash maculo-papular23.03.13.004--
Renal failure20.01.03.005--Not Available
Rhabdomyolysis15.05.05.002--
Seizure17.12.03.001--
Serum sickness12.02.08.004; 10.01.03.004--
Serum sickness-like reaction10.01.03.005; 08.01.03.003--Not Available
Shock24.06.02.002--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Stevens-Johnson syndrome23.03.01.007; 12.03.01.014; 11.07.01.005; 10.01.03.020--
Stomatitis07.05.06.005--
Suffocation feeling22.02.08.012--Not Available
Thrombocytopenia01.08.01.002--Not Available
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