| Drug Name |
Azithromycin monohydrate |
| Drug ID |
BADD_D00205 |
| Description |
Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration [A174172]. It was initially approved by the FDA in 1991 [A174175].
It is primarily used for the treatment of respiratory, enteric and genitourinary infections and may be used instead of other macrolides for some sexually transmitted and enteric infections. It is structurally related to erythromycin [A174169].
Azithromycin [9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin] is a part of the _azalide_ subclass of macrolides, and contains a 15-membered ring, with a methyl-substituted nitrogen instead of a carbonyl group at the 9a position on the aglycone ring, which allows for the prevention of its metabolism. This differentiates azithromycin from other types of macrolides [A174175].
In March 2020, a small study was funded by the French government to investigate the treatment of COVID-19 with a combination of azithromycin and the anti-malaria drug [hydroxychloroquine]. The results were positive, all patients taking the combination were virologically cured within 6 days of treatment, however, larger studies are required.[A192546] |
| Indications and Usage |
For the treatment of patients with mild to moderate infections caused by susceptible strains of the designated microorganisms in the specific conditions: H. influenzae, M. catarrhalis, S. pneumoniae, C. pneumoniae, M. pneumoniae, S. pyogenes, S. aureus, S. agal |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
J01FA10; S01AA26 |
| DrugBank ID |
DB00207
|
| KEGG ID |
D06390
|
| MeSH ID |
D017963
|
| PubChem ID |
9897015
|
| TTD Drug ID |
D03HJK
|
| NDC Product Code |
60687-271; 43063-715; 70860-100; 71205-427; 48792-7870; 65162-708; 68071-3136; 68083-199; 0904-6909; 68180-162; 68180-161; 65162-759; 54348-857; 0527-2395; 63323-398; 0904-6708; 68788-7654; 55154-8094; 60687-282; 71205-119; 48792-7869; 70232-0006; 66639-011; 61919-170; 70518-0803; 65162-758; 70860-125; 43063-713; 0527-2370; 46708-866; 61919-096; 70518-3094; 60687-314; 65372-1106; 53002-3221; 17478-307; 46708-865; 51672-4200; 65162-760; 43063-728; 70518-0736; 68071-3169; 68180-160 |
| Synonyms |
Azithromycin | Azythromycin | Sumamed | Toraseptol | Vinzam | CP-62993 | CP 62993 | CP62993 | Zithromax | Azitrocin | Azadose | Ultreon | Zitromax | Azithromycin Dihydrate | Dihydrate, Azithromycin | Azithromycin Monohydrate | Monohydrate, Azithromycin | Goxal | Zentavion |
