| ADR Ontology |
| ADR Term |
Infantile spasms |
| ADR ID |
BADD_A07316 |
| ADR Hierarchy |
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| Description |
An epileptic syndrome characterized by the triad of infantile spasms, hypsarrhythmia, and arrest of psychomotor development at seizure onset. The majority present between 3-12 months of age, with spasms consisting of combinations of brief flexor or extensor movements of the head, trunk, and limbs. The condition is divided into two forms: cryptogenic (idiopathic) and symptomatic (secondary to a known disease process such as intrauterine infections; nervous system abnormalities; BRAIN DISEASES, METABOLIC, INBORN; prematurity; perinatal asphyxia; TUBEROUS SCLEROSIS; etc.). (From Menkes, Textbook of Child Neurology, 5th ed, pp744-8) [MeSH] |
| MedDRA Code |
10021750 |
| MeSH ID |
D013036; D013036; D013036
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ADR Severity Grade (FAERS)
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ADR Severity Grade (CTCAE)
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Not Available
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| Synonym |
| Hypsarrythmia | Infantile spasms | Infantile spasms, with intractable epilepsy | Infantile spasms, without mention of intractable epilepsy | Salaam attacks | Hypsarrhythmia | Salaam's tic | West's syndrome | Spasms, Infantile | Infantile Spasm | Infantile Spasms | Lightning Attacks | Attack, Lightning | Attacks, Lightning | Lightning Attack | West Syndrome | Syndrome, West | Hypsarrhythmias | Jackknife Seizures | Jackknife Seizure | Seizure, Jackknife | Seizures, Jackknife | Symptomatic Infantile Spasms | Infantile Spasm, Symptomatic | Infantile Spasms, Symptomatic | Spasm, Symptomatic Infantile | Spasms, Symptomatic Infantile | Symptomatic Infantile Spasm | Symptomatic West Syndrome | Syndrome, Symptomatic West | West Syndrome, Symptomatic | Salaam Attacks | Attacks, Salaam | Salaam Seizures | Seizures, Salaam | Spasmus Nutans | Cryptogenic Infantile Spasms | Cryptogenic Infantile Spasm | Infantile Spasm, Cryptogenic | Infantile Spasms, Cryptogenic | Spasm, Cryptogenic Infantile | Spasms, Cryptogenic Infantile | Cryptogenic West Syndrome | Syndrome, Cryptogenic West | West Syndrome, Cryptogenic | Nodding Spasm | Nodding Spasms | Spasm, Nodding | Spasms, Nodding |
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| ADR Related Proteins |
| Protein Name |
UniProt AC |
TTD Target ID |
| Not Available | Not Available | Not Available |
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| Drugs Leading to the ADR |
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