| ADR Ontology |
| ADR Term |
Focal segmental glomerulosclerosis |
| ADR ID |
BADD_A06461 |
| ADR Hierarchy |
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| Description |
A clinicopathological syndrome or diagnostic term for a type of glomerular injury that has multiple causes, primary or secondary. Clinical features include PROTEINURIA, reduced GLOMERULAR FILTRATION RATE, and EDEMA. Kidney biopsy initially indicates focal segmental glomerular consolidation (hyalinosis) or scarring which can progress to globally sclerotic glomeruli leading to eventual KIDNEY FAILURE. | Segmental glomerular degeneration with a glassy appearance (hyalinosis) caused by the accumulation of plasma proteins in the glomeruli. [MeSH] |
| MedDRA Code |
10067757 |
| MeSH ID |
D005923; D005923; D005923
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ADR Severity Grade (FAERS)
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ADR Severity Grade (CTCAE)
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Not Available
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| Synonym |
| Focal & segmental glomerulosclerosis | Focal glomerulosclerosis | Focal segmental glomerulosclerosis | Glomerulosclerosis, Focal Segmental | Segmental Glomerulosclerosis, Focal | Glomerulosclerosis, Focal | Focal Glomerulosclerosis | Focal Segmental Glomerulosclerosis | Glomerulonephritis, Focal Sclerosing | Focal Sclerosing Glomerulonephritides | Focal Sclerosing Glomerulonephritis | Glomerulonephritides, Focal Sclerosing | Sclerosing Glomerulonephritides, Focal | Sclerosing Glomerulonephritis, Focal | Hyalinosis, Segmental Glomerular | Glomerular Hyalinosis, Segmental | Segmental Glomerular Hyalinosis | Hyalinosis, Segmental | Segmental Hyalinosis |
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| ADR Related Proteins |
| Protein Name |
UniProt AC |
TTD Target ID |
| Not Available | Not Available | Not Available |
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| Drugs Leading to the ADR |
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