Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Orchitis
ADR ID BADD_A03205
ADR Hierarchy
11      Infections and infestations
11.01      Infections - pathogen unspecified
11.01.19      Male reproductive tract infections
11.01.19.004      Orchitis
21      Reproductive system and breast disorders
21.09      Male reproductive tract infections and inflammations
21.09.02      Testicular and epididymal infections and inflammations
21.09.02.002      Orchitis
Description Inflammation of a TESTIS. It has many features of EPIDIDYMITIS, such as swollen SCROTUM; PAIN; PYURIA; and FEVER. It is usually related to infections in the URINARY TRACT, which likely spread to the EPIDIDYMIS and then the TESTIS through either the VAS DEFERENS or the lymphatics of the SPERMATIC CORD. [MeSH]
MedDRA Code 10031064
MeSH ID D009920
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Acute epididymo-orchitis | Chronic epididymo-orchitis | Epididymo-orchitis | Epididymo-orchitis NOS | Orchitis | Orchitis and epididymitis | Orchitis and epididymitis in diseases classified elsewhere | Orchitis and epididymitis, unspecified | Orchitis NOS | Orchitis, epididymitis, and epididymo-orchitis, with abscess | Other orchitis, epididymitis, and epididymo-orchitis, without mention of abscess | Other specified orchitis, epididymitis, and epididymo-orchitis, without mention of abscess | Testicular infection | Orchitides
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00115Amiodarone0.000595%
BADD_D00207Bacillus calmette-guerin--
BADD_D00303Bromocresol green--
BADD_D00405Ceftriaxone0.020426%
BADD_D00765Empagliflozin0.001872%
BADD_D00898Finasteride0.001497%
BADD_D00932Fluoxetine--
BADD_D01119Ibrutinib0.000533%
BADD_D01309Lomefloxacin--
BADD_D01310Lomefloxacin hydrochloride--
BADD_D01470Minocycline0.000518%
BADD_D01633Oxaliplatin0.000799%
BADD_D01817Pramipexole--
BADD_D01818Pramipexole dihydrochloride--
BADD_D01835Pregabalin--
BADD_D01888Quetiapine--
BADD_D01889Quetiapine fumarate--
BADD_D01898Rabeprazole--
BADD_D01933Ribavirin0.036262%
BADD_D02192Thalidomide--
BADD_D02236Tofacitinib0.001158%
BADD_D02346Venlafaxine--
BADD_D02464Fingolimod0.001737%
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