Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Exomphalos
ADR ID BADD_A01559
ADR Hierarchy
03      Congenital, familial and genetic disorders
03.04      Gastrointestinal tract disorders congenital
03.04.07      Gastrointestinal tract disorders congenital NEC
03.04.07.001      Exomphalos
07      Gastrointestinal disorders
07.16      Abdominal hernias and other abdominal wall conditions
07.16.03      Umbilical hernias
07.16.03.002      Exomphalos
Description A HERNIA due to an imperfect closure or weakness of the umbilical ring. It appears as a skin-covered protrusion at the UMBILICUS during crying, coughing, or straining. The hernia generally consists of OMENTUM or SMALL INTESTINE. The vast majority of umbilical hernias are congenital but can be acquired due to severe abdominal distention. | A congenital defect with major fissure in the ABDOMINAL WALL at the UMBILICUS resulting in the extrusion of VISCERA through the UMBILICUS. Unlike GASTROSCHISIS, omphalocele is covered with PERITONEUM but without overlying SKIN. [MeSH]
MedDRA Code 10015677
MeSH ID D006554; D006554; D006554
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Exomphalos | Omphalocele | Omphalocoele | Hernia, Umbilical | Umbilical Hernia | Hernias, Umbilical | Umbilical Hernias | Omphaloceles
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00144Antagon--
BADD_D00497Clomiphene--
BADD_D00498Clomiphene citrate--
BADD_D00680Dimethyl fumarate0.000478%
BADD_D00809Escitalopram0.000025%
BADD_D00932Fluoxetine0.000227%
BADD_D01005Ganirelix acetate--
BADD_D01136Imatinib0.000208%
BADD_D01243Lamotrigine0.000773%
BADD_D01265Levetiracetam0.000199%
BADD_D01401Metformin0.000052%
BADD_D01414Methimazole0.002707%
BADD_D01627Oseltamivir0.000145%
BADD_D01679Paroxetine0.000841%
BADD_D01869Propylthiouracil0.010931%
BADD_D01942Riluzole--
BADD_D01952Ritonavir0.000878%
BADD_D02010Sertraline0.000032%
BADD_D02319Urofollitropin--
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