Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Oxygen
Drug ID BADD_D02471
Description Oxygen is an element displayed by the symbol O, and atomic number 8. It is an essential element for human survival. Decreased oxygen levels may be treated with medical oxygen therapy. Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing blood flow resistance in the diseased lung, leading to decreased cardiovascular workload in an attempt to oxygenate the lungs. Oxygen therapy is used to treat emphysema, pneumonia, some heart disorders (congestive heart failure), some disorders that cause increased pulmonary artery pressure, and any disease that impairs the body's ability to take up and use gaseous oxygen. Higher level of oxygen than ambient air (hyperoxia) can be introduced under normobaric or hyperbaric conditions.
Indications and Usage Oxygen therapy in clinical settings is used across diverse specialties, including various types of anoxia, hypoxia or dyspnea and any other disease states and conditions that reduce the efficiency of gas exchange and oxygen consumption such as respiratory illnesses, trauma, poisonings and drug overdoses. Oxygen therapy tries to achieve hyperoxia [L745] to reduce the extent of hypoxia-induced tissue damage and malfunction.
Marketing Status approved; vet_approved
ATC Code V03AN01
DrugBank ID DB09140
KEGG ID D00003
MeSH ID D010100
PubChem ID 977
TTD Drug ID Not Available
NDC Product Code 72661-123; 73055-001; 73087-001; 74795-001; 81426-001; 82043-001; 82666-001; 10073-111; 10927-003; 14214-0123; 19218-0005; 23390-1020; 27561-001; 33335-001; 44076-010; 49575-001; 49696-622; 51791-001; 51887-720; 51960-001; 52003-011; 53425-001; 54202-001; 54528-001; 55050-0011; 55404-001; 57799-001; 58755-0001; 59190-416; 59247-001; 59336-001; 60539-001; 60875-100; 61567-001; 61834-0001; 61888-0202; 62045-4333; 63144-001; 64673-001; 64673-002; 64944-0001; 65010-002; 65119-345; 65297-001; 65898-001; 66487-001; 66878-001; 67525-100; 70101-001; 70513-001; 70951-123; 72712-001; 72739-001; 72746-0001; 72753-001; 72973-001; 73039-001; 73052-001; 73422-001; 74301-001; 74709-001; 75892-001; 77673-001; 10526-005; 13859-001; 14784-001; 15055-001; 19218-0001; 19218-0003; 20479-0682; 21221-002; 24598-0121; 40097-001; 46123-045; 48663-0001; 49479-722; 53952-001; 54384-1073; 54706-0001; 58311-1000; 58700-001; 62447-0011; 62481-4565; 64140-101; 64395-0001; 64464-001; 64545-0001; 64673-005; 65076-101; 65868-001; 66698-001; 66961-100; 69847-001; 70313-001; 72706-123; 72740-123; 72808-001; 72995-001; 73093-001; 10018-8999; 11401-6994; 11988-001; 12121-001; 14080-001; 18482-018; 19979-000; 21624-001; 23650-001; 31462-001; 35420-123; 42602-001; 44356-0001; 51194-123; 51996-001; 52374-101; 53440-001; 53683-0001; 53777-001; 53835-001; 58125-0001; 58662-0001; 59522-001; 60980-002; 61128-001; 61393-0003; 62046-001; 62137-002; 63418-0001; 63674-001; 63817-123; 64763-099; 65217-0001; 66083-741; 66586-1073; 67480-001; 67573-0103; 69240-001; 70300-001; 54244-001; 55037-113; 55127-001; 57837-001; 58128-0001; 58166-001; 58722-9094; 58960-001; 59534-001; 62066-001; 62363-001; 62371-1234; 62486-130; 62914-1000; 63553-001; 64075-123; 64169-001; 64650-345; 65257-001; 66365-001; 66754-001; 66767-999; 67899-001; 69024-001; 70273-001; 72862-001; 73266-001; 76349-001; 80421-100; 81287-001; 82992-001; 10014-001; 10690-001; 11564-001; 13633-001; 14961-006; 17575-001; 19218-0004; 19218-0008; 19218-0009; 33758-001; 43208-001; 43621-001; 44363-1815; 44668-001; 47632-0030; 49944-001; 50322-005; 50597-001; 52481-2481; 53452-001; 53511-001; 55147-001; 5575-0001; 55858-001; 57924-001; 58089-001; 58276-015; 58498-123; 60596-1072; 61362-2150; 61398-0828; 61420-0001; 61520-001; 61830-001; 61869-0001; 62097-9937; 63121-123; 63961-100; 64091-0001; 64304-4304; 64319-001; 64673-004; 64673-006; 65208-123; 65551-001; 65915-123; 67493-0009; 68352-001; 68639-0001; 68794-001; 68877-001; 72574-001; 72718-123; 72723-123; 72817-001; 73012-001; 73543-001; 73544-001; 75828-001; 75930-001; 80650-001; 83508-301; 10304-463; 11043-001; 11748-010; 11928-002; 14269-001; 16175-0001; 16913-0001; 19188-123; 20703-002; 23647-001; 34940-004; 48546-0006; 49344-0001; 50153-110; 50554-100; 51012-001; 51051-003; 51400-001; 53720-001; 54131-001; 54218-500; 54513-001; 55703-001; 57366-0001; 57716-001; 59924-001; 60568-123; 60696-1234; 60768-001; 60833-001; 61865-001; 62273-001; 63560-001; 63978-001; 64203-020; 64889-0001; 65386-0001; 66824-001; 67133-001; 68470-1001; 70672-001; 71408-001; 72660-001; 72710-123; 72755-123; 72757-001; 72986-001; 82401-001; 10412-0001; 10451-001; 10942-2001; 14208-532; 14217-001; 18087-0001; 19218-0007; 40054-1003; 42007-0001; 42389-001; 46123-001; 47632-0029; 48546-0002; 48599-345; 49154-001; 50505-001; 50693-276; 50699-1072; 52568-001; 53622-001; 53730-001
UNII S88TT14065
Synonyms Oxygen | Oxygen-16 | Oxygen 16 | Dioxygen
Chemical Information
Molecular Formula O2
CAS Registry Number 7782-44-7
SMILES O=O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Visual acuity reduced06.02.10.012; 17.17.01.0110.002726%
Vomiting07.01.07.003--
Wheezing22.03.01.0090.001859%
Pneumoperitoneum07.07.01.0080.001859%Not Available
Peripheral swelling08.01.03.053; 02.05.04.015--Not Available
General physical health deterioration08.01.03.018--Not Available
Pneumomediastinum22.09.03.0040.004337%Not Available
Cytokine release syndrome10.02.01.0100.001859%
Diastolic dysfunction02.04.02.0220.001239%Not Available
Bronchopleural fistula22.05.03.0010.001239%
Lung neoplasm malignant22.08.01.001; 16.19.02.001--Not Available
Cluster headache17.14.01.0030.001239%Not Available
Cardiac disorder02.11.01.0030.001859%Not Available
Infarction24.04.02.0170.001239%Not Available
Mental disorder19.07.01.0020.001239%Not Available
Obstructive airways disorder22.03.01.0110.003346%Not Available
Pulmonary toxicity22.01.02.007; 12.03.01.0130.002478%Not Available
Hypophagia14.03.01.006; 07.01.06.010; 19.09.01.0040.001239%Not Available
Pulmonary arterial hypertension24.08.03.003; 22.06.01.0020.001239%Not Available
Liver injury12.01.17.012; 09.01.07.022--Not Available
Brain injury19.07.03.007; 17.11.01.0030.001239%Not Available
Acute kidney injury20.01.03.0160.002478%
Injury associated with device12.01.08.035; 08.07.01.0120.001239%Not Available
Glassy eyes08.01.03.055; 06.08.03.021--Not Available
Multiple organ dysfunction syndrome08.01.03.0570.003717%
Chronic respiratory failure22.02.06.005; 14.01.04.0050.001859%Not Available
Pulmonary artery thrombosis24.01.06.005; 22.06.02.0050.001239%Not Available
Spinal cord ischaemia24.04.06.040; 17.10.01.0180.001859%Not Available
Tobacco interaction08.06.03.0070.001239%Not Available
Pseudomyopia06.02.04.0110.001239%Not Available
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