Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Aclidinium
Drug ID BADD_D02465
Description Aclidinium is an anticholinergic for the long-term management of chronic obstructive pulmonary disease (COPD). It has a much higher propensity to bind to muscarinic receptors than nicotinic receptors. FDA approved on July 24, 2012.
Indications and Usage Aclidinium bromide inhalation powder is indicated for the long-term, maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.
Marketing Status Not Available
ATC Code Not Available
DrugBank ID DB08897
KEGG ID Not Available
MeSH ID Not Available
PubChem ID 11434515
TTD Drug ID D0VP1V
NDC Product Code Not Available
Synonyms Not Available
Chemical Information
Molecular Formula C26H30NO4S2+
CAS Registry Number 727649-81-2
SMILES C1C[N+]2(CCC1C(C2)OC(=O)C(C3=CC=CS3)(C4=CC=CS4)O)CCCOC5=CC=CC=C5
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Agitation19.06.02.001; 17.02.05.0120.001989%
Angioedema23.04.01.001; 10.01.05.0090.001989%Not Available
Anxiety19.06.02.002--
Arrhythmia02.03.02.0010.001989%Not Available
Asthenia08.01.01.0010.003979%Not Available
Asthma22.03.01.002; 10.01.03.0100.006963%Not Available
Blood cholesterol increased13.12.01.0020.001989%
Bronchitis22.07.01.001; 11.01.09.0010.001989%
Bronchospasm22.03.01.004; 10.01.03.0120.005968%
Bronchospasm paradoxical22.03.01.0060.001989%Not Available
Chest discomfort22.02.08.001; 08.01.08.019; 02.02.02.0090.001989%Not Available
Chest pain22.02.08.003; 08.01.08.002; 02.02.02.0110.001989%Not Available
Chronic obstructive pulmonary disease22.03.01.0070.004930%Not Available
Confusional state17.02.03.005; 19.13.01.0010.004973%
Cough22.02.03.0010.003979%
Deafness04.02.01.0010.001989%Not Available
Death08.04.01.001--
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.0040.006963%
Dysgeusia17.02.07.003; 07.14.03.0010.007957%
Dysphonia17.02.08.004; 22.02.05.005; 19.19.03.0020.003979%
Dyspnoea22.02.01.004; 02.01.03.0020.063660%
Dyspnoea exertional22.02.01.005; 02.01.03.0030.001989%Not Available
Epistaxis24.07.01.005; 22.04.03.0010.001989%
Fatigue08.01.01.002--
Feeling abnormal08.01.09.0140.001989%Not Available
Glossodynia07.14.02.0010.001989%Not Available
Headache17.14.01.001--
Hypersensitivity10.01.03.0030.003979%
Hypertension24.08.02.0010.002984%
Hyperventilation22.02.01.006; 19.01.02.0040.001989%Not Available
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