Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Zaleplon
Drug ID BADD_D02379
Description Zaleplon is a sedative/hypnotic, mainly used for insomnia. It is known as a nonbenzodiazepine hypnotic. Zaleplon interacts with the GABA receptor complex and shares some of the pharmacological properties of the benzodiazepines. Zaleplon is a schedule IV drug in the United States.
Indications and Usage For the treatment of short-term treatment of insomnia in adults.
Marketing Status approved; illicit; investigational
ATC Code N05CF03
DrugBank ID DB00962
KEGG ID D00530
MeSH ID C085665
PubChem ID 5719
TTD Drug ID D09DWL
NDC Product Code 29300-131; 71335-1054; 71335-1387; 43063-783; 57237-239; 42043-210; 57237-240; 68788-7208; 53296-0056; 65862-215; 71335-0236; 0054-0085; 63629-3405; 65862-214; 16436-0056; 42043-211; 0054-0084; 71335-1466; 51846-1026; 65862-197; 29300-132; 43063-505; 43063-912; 45865-541; 64330-054
UNII S62U433RMH
Synonyms zaleplon | 3'-(3-cyanopyrazolo(1,5-alpha)pyrimidin-7-yl)-N-ethylacetanilide | N-(3-(3-cyanopyrazolo(1,5-a)pyrimidin-7-yl)phenyl)-N-ethylacetamide | L 846 | L-846 | Zelepion | Starnoc | SKP-1041 | CL 284,846 | CL-284846 | CL284,846 | CL 284846 | Sonata
Chemical Information
Molecular Formula C17H15N5O
CAS Registry Number 151319-34-5
SMILES CCN(C1=CC=CC(=C1)C2=CC=NC3=C(C=NN23)C#N)C(=O)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Eructation07.01.02.003--
Euphoric mood19.04.02.006--
Extrasystoles02.03.02.003--Not Available
Eye disorder06.08.03.001--Not Available
Eye haemorrhage12.02.02.012; 24.07.05.002; 06.07.02.001--Not Available
Eye pain06.08.03.002--
Eyelid ptosis17.17.02.004; 06.05.01.002--Not Available
Face oedema08.01.07.003; 23.04.01.004; 10.01.05.002--
Facial paralysis17.04.03.008--Not Available
Feeling abnormal08.01.09.014--Not Available
Flat affect19.04.01.004--Not Available
Flatulence07.01.04.002--
Fluid retention20.01.02.003; 14.05.06.002--Not Available
Gait disturbance15.03.05.013; 17.02.05.016; 08.01.02.002--
Gastritis07.08.02.001--
Gastroenteritis11.01.07.004; 07.19.03.001--Not Available
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal pain07.01.05.005--
Generalised oedema14.05.06.007; 08.01.07.004--
Gingival bleeding24.07.02.010; 07.09.07.001--Not Available
Gingivitis07.09.10.002; 11.01.04.013--
Glaucoma06.03.01.002--
Glossitis07.14.01.001--Not Available
Goitre14.11.01.008; 05.02.01.001--Not Available
Gout15.01.06.001; 14.09.01.001--Not Available
Haematuria21.10.01.018; 20.02.01.006; 24.07.01.047--
Hallucination19.10.04.003--
Hangover08.01.09.018--Not Available
Headache17.14.01.001--
Hepatotoxicity12.03.01.008; 09.01.07.009--Not Available
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ADReCS-Target
Drug Name ADR Term Target
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