Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Valganciclovir
Drug ID BADD_D02326
Description Valganciclovir hydrochloride (Valcyte, manufactured by Roche) is an antiviral medication used to treat cytomegalovirus infections. As the L-valyl ester of ganciclovir, it is actually a prodrug for ganciclovir. After oral administration, it is rapidly converted to ganciclovir by intestinal and hepatic esterases.
Indications and Usage Valganciclovir is an antiviral medication used for the treatment of cytomegalovirus infections.
Marketing Status Prescription
ATC Code J05AB14
DrugBank ID DB01610
KEGG ID D02495
MeSH ID D000077562
PubChem ID 135413535
TTD Drug ID D06GWF
NDC Product Code 55111-762; 60429-846; 63739-076; 27241-158; 16714-765; 70010-051; 0004-0038; 50268-787; 71151-003; 31722-832; 69097-277; 0904-6796; 48433-124; 68084-965; 70069-810
Synonyms Valganciclovir | Ganciclovir L-valyl Ester | Ganciclovir L valyl Ester | Valcyt | Valganciclovir Hydrochloride | Valcyte
Chemical Information
Molecular Formula C14H22N6O5
CAS Registry Number 175865-60-8
SMILES CC(C)C(C(=O)OCC(CO)OCN1C=NC2=C1N=C(NC2=O)N)N
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hypertonia17.05.02.001; 15.05.04.007--Not Available
Hypocalcaemia14.04.01.004--
Hypokalaemia14.05.03.002--
Hypomagnesaemia14.04.02.001--
Hypophosphataemia14.04.03.001--
Hypoproteinaemia09.01.02.004; 14.10.01.003--Not Available
Hypotension24.06.03.002--
Immune system disorder10.02.01.001--Not Available
Infection11.01.08.0020.001916%Not Available
Infertility21.03.02.001--Not Available
Influenza22.07.02.001; 11.05.03.001--Not Available
Influenza like illness08.01.03.010--
Insomnia17.15.03.002; 19.02.01.002--
Jaundice23.03.03.030; 09.01.01.004; 01.06.04.004--Not Available
Kaposi's sarcoma16.33.02.001; 11.05.17.001--Not Available
Laboratory test abnormal13.18.01.0010.004896%Not Available
Leukocytosis01.02.01.002--
Leukopenia01.02.02.0010.012239%Not Available
Libido decreased21.03.02.005; 19.08.03.001--
Localised infection11.01.08.006--Not Available
Lymphadenopathy01.09.01.002--Not Available
Macular oedema06.04.06.0050.004896%Not Available
Malaise08.01.01.0030.014687%
Mental disability26.01.01.001--Not Available
Migraine17.14.02.001; 24.03.05.003--Not Available
Mouth ulceration07.05.06.004--Not Available
Mucous membrane disorder08.01.06.004--Not Available
Muscle spasms15.05.03.004--
Musculoskeletal pain15.03.04.007--
Myasthenic syndrome16.32.01.002; 17.05.04.004; 15.05.08.003; 10.04.05.005--Not Available
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