Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Triazolam
Drug ID BADD_D02277
Description Withdrawn in the United Kingdom due to risk of psychiatric adverse drug reactions. This drug continues to be available in the U.S. Internationally, triazolam is a Schedule IV drug under the Convention on Psychotropic Substances.
Indications and Usage For the short-term treatment of insomnia.
Marketing Status Prescription; Discontinued
ATC Code N05CD05
DrugBank ID DB00897
KEGG ID D00387
MeSH ID D014229
PubChem ID 5556
TTD Drug ID D0U3LS
NDC Product Code 0009-0017; 55289-787; 67763-128; 0054-4858; 0009-5188; 50742-645; 59762-3718; 50742-646; 71335-1876; 59762-3717; 50090-4733; 12828-0041; 0054-4859; 43063-996; 50090-0522; 42816-0017; 43353-451; 63629-2956
Synonyms Triazolam | U-33,030 | U 33,030 | U33,030 | Halcion | Trilam | Apo-Triazo | Apo Triazo | Gen-Triazolam | Gen Triazolam
Chemical Information
Molecular Formula C17H12Cl2N4
CAS Registry Number 28911-01-5
SMILES CC1=NN=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hallucination, visual19.10.02.0040.001847%Not Available
Headache17.14.01.001--
Hepatic failure09.01.03.002--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
Hypokinesia17.01.02.0090.004616%Not Available
Hyponatraemia14.05.04.0020.001847%
Hypothermia12.05.03.001; 08.05.01.0030.001847%
Incontinence20.02.02.004; 17.05.01.006; 07.01.06.011--Not Available
Insomnia19.02.01.002; 17.15.03.002--
Intentional self-injury12.01.08.036; 19.12.01.0020.020312%Not Available
Irritability19.04.02.013; 08.01.03.0110.001847%
Jaundice23.03.03.030; 09.01.01.004; 01.06.04.004--Not Available
Loss of consciousness17.02.04.0040.021236%Not Available
Lymphocyte count13.01.06.037--Not Available
Malaise08.01.01.003--
Mania19.16.02.002--
Memory impairment17.03.02.003; 19.20.01.0030.001847%
Menstruation irregular21.01.01.005; 05.05.01.008--
Mental disability26.01.01.001--Not Available
Miosis17.02.11.002; 06.05.03.0030.003693%Not Available
Monocyte count13.01.06.045--Not Available
Mood swings19.04.03.001--Not Available
Movement disorder17.01.02.0100.002770%Not Available
Muscle spasms15.05.03.004--
Muscle spasticity15.05.04.011; 17.05.03.007--
Muscular weakness17.05.03.005; 15.05.06.001--
Nausea07.01.07.001--
Nervousness19.06.02.003--Not Available
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