Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Trandolaprilat
Drug ID BADD_D02260
Description The active metabolite of the prodrug [Trandolapril].
Indications and Usage Not Available
Marketing Status experimental
ATC Code Not Available
DrugBank ID DB14209
KEGG ID Not Available
MeSH ID C061095
PubChem ID 5464097
TTD Drug ID Not Available
NDC Product Code Not Available
UNII RR6866VL0O
Synonyms trandolaprilat | 1-(2-((1-carboxy-3-phenylpropyl)amino)-1-oxopropyl)octahydro-1H-indole-2-carboxylic acid | trandolaprilate | RU 44 403 | RU-44403 | RU 44403 | trandolaprilat, (2S-(1R*(R*)),2alpha,3aalpha,7abeta)-isomer | trandolaprilat, (2S-(1(R*(R*)),2alpha,3abeta,7abeta))-isomer | trandolaprilat, (2S-(1(S*(R*)),2alpha,3aalpha,7abeta))-isomer
Chemical Information
Molecular Formula C22H30N2O5
CAS Registry Number 87679-71-8
SMILES CC(C(=O)N1C2CCCCC2CC1C(=O)O)NC(CCC3=CC=CC=C3)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Pancreatitis07.18.01.001--
Pancytopenia01.03.03.003--Not Available
Paraesthesia23.03.03.094; 17.02.06.005--
Pemphigus23.03.01.005; 10.04.02.003--Not Available
Pharyngitis22.07.03.004; 11.01.13.003; 07.05.07.004--
Pica19.09.01.009; 14.03.02.014--Not Available
Pruritus23.03.12.001--
Pulmonary eosinophilia22.01.01.009; 01.02.04.006--Not Available
Rash23.03.13.001--Not Available
Renal artery stenosis24.04.11.001; 20.01.07.005--Not Available
Renal failure20.01.03.005--Not Available
Shock24.06.02.002--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Stevens-Johnson syndrome23.03.01.007; 12.03.01.014; 11.07.01.005; 10.01.01.045--
Syncope02.11.04.015; 24.06.02.012; 17.02.04.008--
Tachycardia02.03.02.007--Not Available
Thrombocytopenia01.08.01.002--Not Available
Toxic epidermal necrolysis10.01.01.006; 23.03.01.008; 12.03.01.015; 11.07.01.006--
Transient ischaemic attack24.04.06.005; 17.08.04.001--
Upper respiratory tract infection22.07.03.011; 11.01.13.009--
Ventricular tachycardia02.03.04.010--
Vertigo17.02.12.002; 04.04.01.003--
Vomiting07.01.07.003--
White blood cell count decreased13.01.06.012--
Acute coronary syndrome24.04.04.011; 02.02.02.015--Not Available
Musculoskeletal discomfort15.03.04.001--Not Available
Disturbance in sexual arousal19.08.04.003--Not Available
Hepatic enzyme increased13.03.04.028--Not Available
Erectile dysfunction21.03.01.007; 19.08.04.001--
Ill-defined disorder08.01.03.049--Not Available
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