Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Rizatriptan benzoate
Drug ID BADD_D01958
Description Rizatriptan is a triptan drug used for the treatment of migraine headaches. It is a selective 5-hydroxytryptamine1 receptor subtype agonist.
Indications and Usage For treatment of acute migraine attacks with or without aura.
Marketing Status Prescription; Discontinued
ATC Code N02CC04
DrugBank ID DB00953
KEGG ID D00675
MeSH ID C093622
PubChem ID 77997
TTD Drug ID D0S9MU
NDC Product Code 51991-362; 64220-995; 70518-2957; 50090-3343; 50090-3921; 71335-1283; 63629-7433; 71335-0810; 43817-133; 68462-465; 29300-269; 71205-644; 70518-0509; 59746-415; 65862-625; 67877-262; 71335-1257; 57237-087; 51991-355; 68462-467; 69097-866; 63629-8256; 65862-626; 53747-043; 72189-258; 50090-4619; 65862-600; 43817-135; 69452-157; 71335-1172; 71335-1577; 69097-865; 51991-354; 65862-599; 72189-316; 55111-092; 78206-142; 71205-398; 0378-1403; 65372-1147; 69452-156; 55700-958; 67835-5016; 45865-825; 33342-093; 68462-468; 71335-1346; 57237-088; 53002-3713; 61919-656; 65015-653; 71205-557; 68462-466; 66039-835; 29300-268; 71335-1819; 67877-261; 51991-363; 59746-414; 64567-0013; 57237-085; 57237-086; 0093-7471; 53104-7580; 63187-563; 14593-872; 50090-3367; 72189-126; 29300-317; 33342-094; 0378-1404; 55700-942; 61919-394; 29300-316; 59746-446; 59746-445; 0093-7472; 78206-143; 71335-1912; 71335-1149; 64220-996; 53002-1713; 65862-578; 63629-8122; 71335-2031
Synonyms rizatriptan | N,N-dimethyl-2-(5-(1,2,4-triazol-1-ylmethyl)-1H-indole-3-yl)ethylamine | rizatriptan benzoate | MK 0462 | MK-0462 | MK-462 | MK 462 | L 705,126 | L-705,126 | L-705126 | L 705126 | Maxalt
Chemical Information
Molecular Formula C22H25N5O2
CAS Registry Number 145202-66-0
SMILES CN(C)CCC1=CNC2=C1C=C(C=C2)CN3C=NC=N3.C1=CC=C(C=C1)C(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Eye swelling06.08.03.003--Not Available
Face oedema23.04.01.004; 10.01.05.002; 08.01.07.003--
Facial pain08.01.08.012--
Fatigue08.01.01.002--
Feeling hot08.01.09.009--Not Available
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
Gait disturbance08.01.02.002; 17.02.05.016--
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal pain07.01.05.005--
Hallucination19.10.02.002--
Headache17.14.01.001--
Hyperhidrosis08.01.03.028; 23.02.03.004--
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
Hypoaesthesia17.02.06.023--Not Available
Insomnia19.02.01.002; 17.15.03.002--
Loss of consciousness17.02.04.004--Not Available
Memory impairment17.03.02.003; 19.20.01.003--
Menopausal symptoms21.02.02.002--Not Available
Muscle spasms15.05.03.004--
Muscular weakness17.05.03.005; 15.05.06.001--
Myalgia15.05.02.001--
Nausea07.01.07.001--
Neck pain15.03.04.009--
Nervousness19.06.02.003--Not Available
Oedema14.05.06.010; 08.01.07.006--Not Available
Pain08.01.08.004--
Pain in jaw15.02.01.003--Not Available
Palpitations02.01.02.003--
Paraesthesia17.02.06.005--
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