Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Riluzole
Drug ID BADD_D01942
Description A glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong the survival of patients with amyotrophic lateral sclerosis. Riluzole is marketed as Rilutek by Sanofi.
Indications and Usage For the treatment of amyotrophic lateral sclerosis (ALS, Lou Gehrig's Disease)
Marketing Status Prescription
ATC Code N07XX02
DrugBank ID DB00740
KEGG ID D00775
MeSH ID D019782
PubChem ID 5070
TTD Drug ID D0H0KB
NDC Product Code 70515-700; 35709-0003; 10094-350; 42291-775; 65129-1011; 63537-0066; 62756-983; 70726-0303; 68462-381; 0378-4145; 62756-538; 67877-286; 69076-200; 65977-0045; 63278-1076; 66039-812; 70510-2201
Synonyms Riluzole | 2-Amino-6-trifluoromethoxybenzothiazole | 2 Amino 6 trifluoromethoxybenzothiazole | Rilutek | RP-54274 | RP 54274 | RP54274 | PK-26124 | PK 26124 | PK26124
Chemical Information
Molecular Formula C8H5F3N2OS
CAS Registry Number 1744-22-5
SMILES C1=CC2=C(C=C1OC(F)(F)F)SC(=N2)N
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hepatitis acute09.01.07.005--Not Available
Hepatocellular injury09.01.07.008--Not Available
Hernia08.01.04.001--Not Available
Hiccups22.02.04.002; 07.01.06.009--
Hostility19.05.01.003--Not Available
Hyperacusis04.02.02.001; 17.04.03.003--Not Available
Hypercalcaemia14.04.01.003; 05.04.01.002--
Hypercholesterolaemia14.08.01.001--Not Available
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypersensitivity10.01.03.0030.002614%
Hypertension24.08.02.001--
Hypertonia17.05.02.001; 15.05.04.007--Not Available
Hyperventilation22.02.01.006; 19.01.02.004--Not Available
Hypoaesthesia17.02.06.023--Not Available
Hypochromic anaemia01.03.02.004--Not Available
Hypokalaemia14.05.03.002--
Hypokinesia17.01.02.009--Not Available
Hyponatraemia14.05.04.002--
Hypotension24.06.03.002--
Hypothermia12.05.03.001; 08.05.01.003--
Hypotonia17.05.02.002; 15.05.04.008--Not Available
Hypoventilation22.02.01.007--Not Available
Hypoxia22.02.02.003--
Ileus07.13.01.001--
Immune system disorder10.02.01.001--Not Available
Increased appetite14.03.01.003; 08.01.09.027--Not Available
Infection11.01.08.002--Not Available
Influenza22.07.02.001; 11.05.03.001--Not Available
Injection site reaction12.07.03.015; 08.02.03.014--
Injury12.01.08.004--Not Available
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