| Drug Name |
Pregabalin |
| Drug ID |
BADD_D01835 |
| Description |
Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter.[A173995] It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other conditions.[A187190] Although as per the FDA Label the mechanism of action has not been definitively defined, there is evidence that pregabalin exerts its effects by binding to the α2δ subunit of voltage-dependent calcium channels.[A187190][L7066] Pregabalin is marketed by Pfizer under the trade name Lyrica and Lyrica Cr (extended release).[L1006][L7066] It may have dependence liability if misused but the risk appears to be highest in patients with current or past substance use disorders.[A31161] |
| Indications and Usage |
Pregabalin is used for the management of neuropathic pain associated with diabetic peripheral neuropathy or spinal cord injury, and postherpetic neuralgia. It is not approved for the management of fibromyalgia or as adjuntive therapy for adult partial onset seizures.[FDA label] |
| Marketing Status |
Prescription |
| ATC Code |
N03AX16 |
| DrugBank ID |
DB00230
|
| KEGG ID |
D02716
|
| MeSH ID |
D000069583
|
| PubChem ID |
5486971
|
| TTD Drug ID |
D00WUF
|
| NDC Product Code |
69238-1315; 72189-032; 71335-1476; 0228-2860; 59762-1354; 63539-014; 59762-1364; 72189-028; 55700-956; 59762-1348; 64980-413; 71335-1791; 71335-2012; 71335-1744; 76420-124; 55700-827; 0071-1017; 72189-269; 43598-297; 72658-0811; 71205-556; 53869-1473; 80425-0129; 69539-012; 80425-0124; 55700-804; 71335-1745; 72189-035; 72189-023; 76420-099; 69097-957; 69367-326; 60219-1317; 76282-574; 27808-237; 55700-805; 80425-0123; 68788-7524; 76282-572; 76420-097; 76420-100; 59762-1576; 0071-1012; 42419-019; 76420-121; 42385-308; 76420-123; 71205-298; 69097-955; 63629-3369; 64980-414; 71335-1790; 72658-0812; 69097-956; 71205-876; 69097-961; 66174-0031; 69367-329; 72189-251; 80425-0185; 60219-1316; 72189-033; 60219-1314; 66651-915; 0228-2858; 60219-1310; 31722-614; 43598-296; 69238-1317; 72658-0849; 72658-0808; 55154-2431; 76420-118; 31722-615; 72658-0813; 0071-1018; 27808-235; 69539-015; 69367-330; 71610-356; 47781-381; 72606-008; 60687-506; 51407-510; 0228-2861; 0904-7004; 71335-1300; 43353-263; 47335-691; 63304-048; 71335-1822; 69097-954; 0071-1026; 60760-205; 62350-0072; 76420-098; 53869-1016; 55154-2430; 70518-2763; 72189-021; 71335-1505; 60219-1312; 63629-8198; 71335-2015; 71610-316; 53869-1018; 0071-1019; 0904-7005; 71335-2000; 0071-1016; 72888-051; 70518-2571; 71610-351; 0904-7002; 62332-121; 71610-358; 45865-126; 69367-331; 55700-904; 50436-0325; 0904-7003; 71610-331; 63539-024; 68788-7523; 76282-569; 70518-2568; 31722-616; 71610-334; 55700-817; 15894-0016; 71205-875; 71335-1459; 72189-020; 60687-495; 60687-517; 76282-568; 72888-049; 66039-926; 80425-0025; 47335-688; 63629-8196; 69238-1312; 72205-013; 68788-7656; 71205-304; 46708-125; 72658-0814; 69539-128; 70518-2948; 71205-338; 60687-484; 71205-871; 64980-417; 80425-0029; 53869-1014; 71610-365; 80425-0147; 53869-1010; 43353-414; 71610-333; 71610-328; 71335-1792; 63629-4181; 70518-2745; 50228-350; 43598-291; 72643-010; 71335-1758; 60219-1315; 50370-0013; 65015-857; 72189-034; 80425-0026; 66577-034; 80425-0152; 67877-466; 47335-687; 50090-5071; 0228-2862; 67877-465; 76282-573; 55700-964; 63629-8199; 43598-295; 43353-264; 47781-379; 70518-2980; 31722-611; 63629-8208; 60760-486; 64980-412; 16812-003; 70518-2525; 69539-018; 59762-1360; 59285-002; 0071-1027; 0228-2859; 80425-0166; 69238-1314; 60219-1311; 76282-570; 71205-869; 72640-002; 69539-129; 27808-236; 47781-380; 67877-467; 72606-007; 80425-0028; 76420-117; 70518-2762; 53869-1013; 72189-164; 72658-0809; 60760-509; 65862-790; 47335-690; 61919-503; 63629-8197; 71205-323; 80425-0116; 72189-019; 0071-1020; 50090-5038; 50090-5177; 27808-239; 55700-891; 70518-3345; 62332-123; 60219-1313; 70518-2689; 69367-325; 70518-2569; 67877-463; 69238-1311; 71610-317; 69367-328; 50228-355; 51407-511; 68788-7521; 70518-2364; 17337-0421; 70518-2290; 0071-1014; 69539-011; 50228-357; 69097-962; 69097-959; 0071-1013; 71610-335; 43598-294; 55289-257; 71610-319; 43353-675; 76282-575; 46708-120; 71205-396; 55111-882; 0071-1015; 43598-293; 47335-693; 72189-328; 63629-8195; 72189-045; 62332-119; 60687-473; 69238-1310; 59762-1342; 71610-071; 67877-468; 53869-1011; 72205-018; 62332-124; 0228-2857; 71610-329; 45865-108; 71610-330; 71610-361; 71205-608; 72205-017; 50228-354; 71205-873; 67877-462; 71610-357; 31722-612; 43598-298; 72205-012; 63629-8248; 62332-125; 68724-1235; 50228-356; 55289-569; 69238-1316; 60760-507; 59762-1351; 69097-958; 0228-2863; 69238-1313; 50228-351 |
| Synonyms |
Pregabalin | (S)-3-(aminomethyl)-5-methylhexanoic acid | 3-isobutyl GABA | 3 isobutyl GABA | GABA, 3-isobutyl | 3-(aminomethyl)-5-methylhexanoic acid | (R-)-3-isobutyl GABA | (S+)-3-isobutyl GABA | Lyrica | CI 1008 | 1008, CI | CI-1008 | CI1008 |
