Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Prednisolone
Drug ID BADD_D01831
Description Prednisolone is a glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects.[A187463] Prednisolone was granted FDA approval on 21 June 1955.[L9431]
Indications and Usage Prednisolone is indicated to treat endocrine, rheumatic, and hematologic disorders; collagen, dermatologic, ophthalmic, respiratory, and gastrointestinal diseases; allergic and edematous states; and other conditions like tuberculous meningitis.[L9542]
Marketing Status approved; vet_approved
ATC Code A01AC04; A07EA01; C05AA04; D07AA03; D07XA02; H02AB06; R01AD02; S01BA04; S01CB02; S02BA03; S03BA02
DrugBank ID DB00860
KEGG ID D00472
MeSH ID D011239
PubChem ID 5755
TTD Drug ID D0D1SG
NDC Product Code 38779-0150; 64958-0097; 82298-104; 67296-1656; 50383-042; 59651-491; 63187-466; 0527-5406; 65089-0038; 50090-0655; 57582-004; 62135-437; 73534-505; 49452-5980; 82298-105; 82298-106; 60592-911; 60722-3001; 51927-0234; 22552-0052
UNII 9PHQ9Y1OLM
Synonyms Prednisolone | Predate | Predonine | Di-Adreson-F | Di Adreson F | DiAdresonF
Chemical Information
Molecular Formula C21H28O5
CAS Registry Number 50-24-8
SMILES CC12CC(C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Glomerulonephritis membranous20.05.01.0070.000052%Not Available
Glossitis07.14.01.0010.000035%Not Available
Glucose tolerance impaired14.06.02.001; 05.06.02.0010.000315%
Goitre14.11.01.008; 05.02.01.0010.000035%Not Available
Graft versus host disease12.02.09.001; 10.02.01.0270.000122%Not Available
Groin pain15.03.02.0040.000105%Not Available
Guillain-Barre syndrome11.07.01.001; 10.04.10.005; 17.09.01.0010.000122%
Haematemesis24.07.02.011; 07.12.02.0020.000192%Not Available
Haematochezia24.07.02.012; 07.12.02.0030.000332%Not Available
Haematoma24.07.01.0010.000192%
Haematuria21.10.01.018; 24.07.01.047; 20.02.01.0060.000280%
Haemoglobin13.01.05.018--Not Available
Haemolysis01.06.04.0020.000087%
Haemolytic anaemia01.06.03.0020.000175%Not Available
Haemolytic uraemic syndrome20.01.03.011; 01.06.02.0010.000052%
Haemorrhage subcutaneous24.07.06.010; 23.06.07.0020.000122%Not Available
Hallucination, auditory19.10.04.0040.000210%Not Available
Hallucination, visual19.10.04.0070.000175%Not Available
Head discomfort17.02.05.0270.000087%Not Available
Headache17.14.01.001--
Hemianopia17.17.01.012; 06.02.07.0040.000035%Not Available
Hemiparesis17.01.04.0010.000192%
Hemiplegia17.01.04.0020.000070%Not Available
Hepatic artery thrombosis24.01.03.002; 09.01.06.0050.000035%Not Available
Hepatic cirrhosis09.01.04.0010.000129%Not Available
Hepatic failure09.01.03.0020.000210%
Hepatic function abnormal09.01.02.0010.000654%Not Available
Hepatic necrosis09.01.07.0020.000035%
Hepatic steatosis14.08.04.005; 09.01.07.0030.000105%Not Available
Hepatitis09.01.07.0040.000192%Not Available
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ADReCS-Target
Drug Name ADR Term Target
Tip:  Drug Name  ADR Term  Protein  Variation  Gene