Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Piroxicam
Drug ID BADD_D01784
Description A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its long half-life enables it to be administered once daily.
Indications and Usage For treatment of osteoarthritis and rheumatoid arthritis.
Marketing Status approved; investigational
ATC Code M01AC01; M02AA07; S01BC06
DrugBank ID DB00554
KEGG ID D00127
MeSH ID D010894
PubChem ID 54676228
TTD Drug ID D00IBN
NDC Product Code 72789-211; 0093-0757; 71335-1999; 51927-1699; 70771-1429; 71335-2067; 72189-350; 22365-114; 59348-0014; 0093-0756; 29033-012; 42543-114; 71335-9622; 17337-0538; 38779-0302; 46438-0053; 49452-5476; 29300-255; 63629-9149; 0069-3220; 42291-674; 55700-697; 0069-3230; 62991-1113; 42291-677; 42571-177; 63629-9148; 71205-032; 72789-210; 59762-0145; 63629-9150; 53747-044; 60715-3270; 59762-0140; 64380-843; 70771-1430; 51927-0145; 60592-604; 63187-972; 64380-842; 71205-203; 46438-0639; 68981-041; 29033-013; 29300-256; 42543-115; 42571-176
UNII 13T4O6VMAM
Synonyms Piroxicam | CP-16171 | CP 16171 | CP16171 | Feldene
Chemical Information
Molecular Formula C15H13N3O4S
CAS Registry Number 36322-90-4
SMILES CN1C(=C(C2=CC=CC=C2S1(=O)=O)O)C(=O)NC3=CC=CC=N3
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Henoch-Schonlein purpura24.07.06.003; 23.06.01.002; 10.02.02.004; 01.01.04.001--Not Available
Hepatic failure09.01.03.002--
Hepatitis09.01.07.0040.002127%Not Available
Hepatocellular injury09.01.07.0080.001595%Not Available
Hepatotoxicity12.03.01.008; 09.01.07.0090.001064%Not Available
Hyperglycaemia14.06.02.002; 05.06.02.002--
Hyperhidrosis23.02.03.004; 08.01.03.0280.002127%
Hyperkalaemia14.05.03.0010.001064%
Hypersensitivity10.01.03.0030.005743%
Hypersensitivity vasculitis10.02.02.017; 01.01.04.008; 24.12.04.013; 23.06.02.0050.001064%Not Available
Hypertension24.08.02.001--
Hyperuricaemia14.09.01.0030.001595%
Hypoaesthesia23.03.03.081; 17.02.06.0230.001064%Not Available
Hypocalcaemia14.04.01.0040.002127%
Hypoglycaemia14.06.03.001; 05.06.03.001--
Hyponatraemia14.05.04.0020.002127%
Hypotension24.06.03.002--
Hypothyroidism14.11.01.012; 05.02.03.0010.001064%
Hypotonia17.05.02.002; 15.05.04.0080.001064%Not Available
Increased appetite14.03.01.003; 08.01.09.027--Not Available
Infection11.01.08.002--Not Available
Influenza like illness08.01.03.010--
Injection site atrophy12.07.03.022; 08.02.03.0220.001064%Not Available
Insomnia19.02.01.002; 17.15.03.002--
Irritability19.04.02.013; 08.01.03.011--
Jaundice23.03.03.030; 09.01.01.004; 01.06.04.004--Not Available
Joint swelling15.01.02.004--Not Available
Leukopenia01.02.02.001--Not Available
Local reaction08.01.03.012--Not Available
Loss of consciousness17.02.04.0040.001064%Not Available
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ADReCS-Target
Drug Name ADR Term Target
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