Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Mycophenolic acid
Drug ID BADD_D01508
Description Mycophenolic acid is an an immunosuppresant drug and potent anti-proliferative, and can be used in place of the older anti-proliferative azathioprine. It is usually used as part of triple therapy including a calcineurin inhibitor (ciclosporin or tacrolimus) and prednisolone. It is also useful in research for the selection of animal cells that express the E. coli gene coding for XGPRT (xanthine guanine phosphoribosyltransferase).
Indications and Usage For the prophylaxis of organ rejection in patients receiving allogeneic renal transplants, administered in combination with cyclosporine and corticosteroids.
Marketing Status approved
ATC Code L04AA06
DrugBank ID DB01024
KEGG ID D05096
MeSH ID D009173
PubChem ID 446541
TTD Drug ID D04FBR
NDC Product Code 72789-246; 68084-918; 70518-3218; 70748-218; 16729-189; 72789-247; 60505-2965; 67877-427; 70436-172; 0904-6785; 0078-0386; 16729-261; 70377-039; 0904-6786; 20076-0405; 50268-559; 60429-016; 60505-2966; 68084-907; 68254-5002; 50090-6492; 0378-4201; 52076-6215; 57885-0009; 60429-017; 67877-426; 70518-3255; 24979-161; 0378-4202; 70436-173; 70748-217; 65727-011; 0078-0385; 24979-160; 68254-5001; 70377-040; 51187-0004
UNII HU9DX48N0T
Synonyms Mycophenolic Acid | Mycophenolate Mofetil | Mofetil, Mycophenolate | Mycophenolic Acid Morpholinoethyl Ester | Cellcept | Mycophenolate Sodium | Sodium Mycophenolate | Mycophenolate, Sodium | Myfortic | Mycophenolate Mofetil Hydrochloride | Mofetil Hydrochloride, Mycophenolate | RS 61443 | RS-61443 | RS61443
Chemical Information
Molecular Formula C17H20O6
CAS Registry Number 24280-93-1
SMILES CC1=C2COC(=O)C2=C(C(=C1OC)CC=C(C)CCC(=O)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Acute kidney injury20.01.03.0160.004280%
Toxicity to various agents12.03.01.046--Not Available
Lacrimal structural disorder06.06.04.013--Not Available
Candida infection11.03.03.021--
Renal transplant failure20.01.02.014; 12.02.09.017; 10.02.03.006--Not Available
Multiple organ dysfunction syndrome08.01.03.0570.001427%
Depersonalisation/derealisation disorder19.14.01.004--Not Available
Ureteric stenosis20.06.01.0100.000951%Not Available
Cell death14.11.02.005; 08.03.03.0030.001427%Not Available
Chronic kidney disease-mineral and bone disorder20.01.01.012; 15.02.03.018; 14.04.04.0170.000951%Not Available
Hernial eventration07.16.06.0100.000951%Not Available
Illness08.01.03.0910.004185%Not Available
Lung transplant rejection12.02.07.015; 10.02.03.011; 22.01.01.0290.000951%Not Available
Myelosuppression01.03.03.0150.002568%Not Available
Oral administration complication08.02.04.035; 12.07.04.0350.001427%Not Available
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ADReCS-Target
Drug Name ADR Term Target
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