Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Mycophenolic acid
Drug ID BADD_D01508
Description Mycophenolic acid is an an immunosuppresant drug and potent anti-proliferative, and can be used in place of the older anti-proliferative azathioprine. It is usually used as part of triple therapy including a calcineurin inhibitor (ciclosporin or tacrolimus) and prednisolone. It is also useful in research for the selection of animal cells that express the E. coli gene coding for XGPRT (xanthine guanine phosphoribosyltransferase).
Indications and Usage For the prophylaxis of organ rejection in patients receiving allogeneic renal transplants, administered in combination with cyclosporine and corticosteroids.
Marketing Status Prescription; Discontinued
ATC Code L04AA06
DrugBank ID DB01024
KEGG ID D05096
MeSH ID D009173
PubChem ID 446541
TTD Drug ID D04FBR
NDC Product Code 70518-3218; 60429-016; 72322-1049; 68084-918; 0904-6785; 60505-2965; 68254-5001; 68254-5002; 0078-0385; 70748-218; 70518-3255; 68084-907; 0904-6786; 24979-160; 50268-559; 51187-0004; 0378-4201; 60505-2966; 67877-426; 52076-6215; 0378-4202; 16729-261; 67877-427; 16729-189; 72322-1048; 70436-172; 60429-017; 24979-161; 20076-0405; 0078-0386; 70436-173; 57885-0009; 65727-011; 70748-217
Synonyms Mycophenolic Acid | Mycophenolate Mofetil | Mofetil, Mycophenolate | Mycophenolic Acid Morpholinoethyl Ester | Cellcept | Mycophenolate Sodium | Sodium Mycophenolate | Mycophenolate, Sodium | Myfortic | Mycophenolate Mofetil Hydrochloride | Mofetil Hydrochloride, Mycophenolate | RS 61443 | RS-61443 | RS61443
Chemical Information
Molecular Formula C17H20O6
CAS Registry Number 24280-93-1
SMILES CC1=C2COC(=O)C2=C(C(=C1OC)CC=C(C)CCC(=O)O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Respiratory tract infection22.07.07.001; 11.01.08.0170.001158%Not Available
Increased bronchial secretion22.02.04.007--Not Available
Blood count abnormal13.01.07.0010.001158%Not Available
Device related infection11.01.08.018; 08.07.01.005--
Chronic kidney disease20.01.03.0170.004053%
Procedural pain12.02.05.007; 08.01.08.009--Not Available
Polyomavirus-associated nephropathy20.01.09.003; 12.02.10.002; 11.05.05.002--Not Available
Bone marrow failure01.03.03.0050.001158%
Urethral stenosis20.07.03.003--Not Available
Liver injury12.01.02.003; 09.01.07.0220.005211%Not Available
Oral herpes07.05.07.002; 11.05.02.0050.001158%Not Available
Oropharyngeal discomfort22.02.05.027; 07.05.05.008--Not Available
Oropharyngeal pain22.02.05.022; 07.05.05.0040.001158%
X-linked lymphoproliferative syndrome10.03.01.003; 03.17.01.002; 01.13.02.003; 16.21.02.003; 11.05.10.005--Not Available
Acute kidney injury20.01.03.0160.004053%
Toxicity to various agents12.03.01.046--Not Available
Lacrimal structural disorder06.06.04.013--Not Available
Candida infection11.03.03.021--
Renal transplant failure12.02.09.017; 10.02.03.006; 20.01.02.014--Not Available
Depersonalisation/derealisation disorder19.14.01.004--Not Available
Cell death08.03.03.003; 14.11.02.0050.001737%Not Available
Abdominal wound dehiscence12.02.03.015; 07.16.05.0060.001158%Not Available
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