Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Mycophenolic acid
Drug ID BADD_D01508
Description Mycophenolic acid is an an immunosuppresant drug and potent anti-proliferative, and can be used in place of the older anti-proliferative azathioprine. It is usually used as part of triple therapy including a calcineurin inhibitor (ciclosporin or tacrolimus) and prednisolone. It is also useful in research for the selection of animal cells that express the E. coli gene coding for XGPRT (xanthine guanine phosphoribosyltransferase).
Indications and Usage For the prophylaxis of organ rejection in patients receiving allogeneic renal transplants, administered in combination with cyclosporine and corticosteroids.
Marketing Status Prescription; Discontinued
ATC Code L04AA06
DrugBank ID DB01024
KEGG ID D05096
MeSH ID D009173
PubChem ID 446541
TTD Drug ID D04FBR
NDC Product Code 70518-3218; 60429-016; 72322-1049; 68084-918; 0904-6785; 60505-2965; 68254-5001; 68254-5002; 0078-0385; 70748-218; 70518-3255; 68084-907; 0904-6786; 24979-160; 50268-559; 51187-0004; 0378-4201; 60505-2966; 67877-426; 52076-6215; 0378-4202; 16729-261; 67877-427; 16729-189; 72322-1048; 70436-172; 60429-017; 24979-161; 20076-0405; 0078-0386; 70436-173; 57885-0009; 65727-011; 70748-217
Synonyms Mycophenolic Acid | Mycophenolate Mofetil | Mofetil, Mycophenolate | Mycophenolic Acid Morpholinoethyl Ester | Cellcept | Mycophenolate Sodium | Sodium Mycophenolate | Mycophenolate, Sodium | Myfortic | Mycophenolate Mofetil Hydrochloride | Mofetil Hydrochloride, Mycophenolate | RS 61443 | RS-61443 | RS61443
Chemical Information
Molecular Formula C17H20O6
CAS Registry Number 24280-93-1
SMILES CC1=C2COC(=O)C2=C(C(=C1OC)CC=C(C)CCC(=O)O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Connective tissue disorder15.06.01.006--Not Available
Eyelid disorder23.03.03.028; 06.08.03.010--Not Available
Foetal disorder18.03.02.001--Not Available
Hereditary disorder03.02.01.007--Not Available
Infestation23.09.05.001; 11.09.01.001--Not Available
Inflammation08.01.05.0070.001158%Not Available
Lung infection22.07.01.008; 11.01.09.0080.002895%
Lymphoproliferative disorder16.21.02.001; 01.13.02.001--Not Available
Malnutrition14.03.02.004--Not Available
Mediastinal disorder22.09.03.001--Not Available
Mental disorder19.07.01.002--Not Available
Upper limb fracture15.08.03.018; 12.04.01.0180.001158%Not Available
Decreased appetite14.03.01.005; 08.01.09.0280.004053%
Central nervous system stimulation25.04.01.001--Not Available
Erectile dysfunction21.03.01.007; 19.08.04.001--
Postoperative wound complication12.02.05.019--Not Available
Ill-defined disorder08.01.03.049--Not Available
Lacrimal disorder06.08.02.005--Not Available
Blood disorder01.05.01.004--Not Available
Immunodeficiency10.03.02.0020.001158%Not Available
Atypical mycobacterial infection11.04.02.002--Not Available
Autoimmune disorder10.04.04.003--
Disease recurrence08.01.03.0500.001737%Not Available
Psychotic disorder19.03.01.002--
Gastrointestinal obstruction07.13.01.005--Not Available
Hepatobiliary disease09.01.08.003--Not Available
Immunosuppression10.03.02.0010.001158%Not Available
Hyperlipidaemia14.08.03.0010.001737%
Urine analysis abnormal13.13.02.008--Not Available
Renal impairment20.01.03.0100.004632%Not Available
The 16th Page    First    Pre   16 17    Next   Last    Total 17 Pages