Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Mycophenolic acid
Drug ID BADD_D01508
Description Mycophenolic acid is an an immunosuppresant drug and potent anti-proliferative, and can be used in place of the older anti-proliferative azathioprine. It is usually used as part of triple therapy including a calcineurin inhibitor (ciclosporin or tacrolimus) and prednisolone. It is also useful in research for the selection of animal cells that express the E. coli gene coding for XGPRT (xanthine guanine phosphoribosyltransferase).
Indications and Usage For the prophylaxis of organ rejection in patients receiving allogeneic renal transplants, administered in combination with cyclosporine and corticosteroids.
Marketing Status approved
ATC Code L04AA06
DrugBank ID DB01024
KEGG ID D05096
MeSH ID D009173
PubChem ID 446541
TTD Drug ID D04FBR
NDC Product Code 72789-246; 68084-918; 70518-3218; 70748-218; 16729-189; 72789-247; 60505-2965; 67877-427; 70436-172; 0904-6785; 0078-0386; 16729-261; 70377-039; 0904-6786; 20076-0405; 50268-559; 60429-016; 60505-2966; 68084-907; 68254-5002; 50090-6492; 0378-4201; 52076-6215; 57885-0009; 60429-017; 67877-426; 70518-3255; 24979-161; 0378-4202; 70436-173; 70748-217; 65727-011; 0078-0385; 24979-160; 68254-5001; 70377-040; 51187-0004
UNII HU9DX48N0T
Synonyms Mycophenolic Acid | Mycophenolate Mofetil | Mofetil, Mycophenolate | Mycophenolic Acid Morpholinoethyl Ester | Cellcept | Mycophenolate Sodium | Sodium Mycophenolate | Mycophenolate, Sodium | Myfortic | Mycophenolate Mofetil Hydrochloride | Mofetil Hydrochloride, Mycophenolate | RS 61443 | RS-61443 | RS61443
Chemical Information
Molecular Formula C17H20O6
CAS Registry Number 24280-93-1
SMILES CC1=C2COC(=O)C2=C(C(=C1OC)CC=C(C)CCC(=O)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Decreased appetite14.03.01.005; 08.01.09.0280.005611%
Central nervous system stimulation25.04.01.001--Not Available
Erectile dysfunction21.03.01.007; 19.08.04.001--
Postoperative wound complication12.02.05.019--Not Available
Ill-defined disorder08.01.03.049--Not Available
Lacrimal disorder06.08.02.005--Not Available
Blood disorder01.05.01.004--Not Available
Immunodeficiency10.03.02.0020.000951%Not Available
Atypical mycobacterial infection11.04.02.002--Not Available
Autoimmune disorder10.04.04.003--
Disease recurrence08.01.03.0500.002568%Not Available
Psychotic disorder19.03.01.002--
Gastrointestinal obstruction07.13.01.005--Not Available
Hepatobiliary disease09.01.08.003--Not Available
Immunosuppression10.03.02.0010.002568%Not Available
Hyperlipidaemia14.08.03.0010.001427%
Urine analysis abnormal13.13.02.008--Not Available
Renal impairment20.01.03.0100.004755%Not Available
Respiratory tract infection22.07.07.001; 11.01.08.017--Not Available
Increased bronchial secretion22.12.01.002--Not Available
Device related infection11.01.08.018; 08.07.01.005--
Chronic kidney disease20.01.03.0170.002378%
Procedural pain12.02.05.007; 08.01.08.009--Not Available
Polyomavirus-associated nephropathy12.02.09.037; 20.01.09.003; 11.05.05.002--Not Available
Bone marrow failure01.03.03.0050.000951%
Urethral stenosis20.07.03.003--Not Available
Liver injury12.01.17.012; 09.01.07.0220.004280%Not Available
Oropharyngeal discomfort22.12.03.015; 07.05.05.008--Not Available
Oropharyngeal pain22.12.03.016; 07.05.05.0040.003234%
X-linked lymphoproliferative syndrome16.21.02.003; 11.05.10.005; 10.03.01.003; 03.17.01.002; 01.13.02.003--Not Available
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ADReCS-Target
Drug Name ADR Term Target
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