| Drug Name |
Misoprostol |
| Drug ID |
BADD_D01477 |
| Description |
Misoprostol is a prostaglandin analog used to reduce the risk of NSAID related ulcers, manage miscarriages, prevent post partum hemorrhage, and also for first trimester abortions.[L7616,L7619,A181589,A181583,A181697] The stimulation of prostaglandin receptors in the stomach reduces gastric acid secretion, while stimulating these receptors in the uterus and cervix can increase the strength and frequency of contractions and decrease cervical tone.[A181586]
Misoprostol was granted FDA approval on 27 December 1988.[L7616] |
| Indications and Usage |
Misoprostol is also indicated for other uses that are not approved in Canada, including the medical termination of an intrauterine pregnancy used alone or in combination with methotrexate,as well as the induction of labour in a selected population of pregnant women with unfavourable cervices. This indication is avoided in women with prior uterine surgery or cesarean surgery due to an increased risk of possible uterine rupture. Misoprostol is also used for the prevention or treatment of serious postpartum hemorrhage. |
| Marketing Status |
Prescription |
| ATC Code |
A02BB01; G02AD06 |
| DrugBank ID |
DB00929
|
| KEGG ID |
D00419
|
| MeSH ID |
D016595
|
| PubChem ID |
5282381
|
| TTD Drug ID |
D09ANG
|
| NDC Product Code |
59762-5007; 0025-1451; 55289-248; 38779-2778; 43393-022; 70710-1006; 0904-6806; 40032-160; 0025-1461; 43063-707; 54348-148; 60592-234; 72789-121; 71335-0460; 70954-443; 72789-111; 72789-128; 40016-002; 43393-020; 40032-161; 70954-444; 65035-103; 43386-161; 68071-4843; 0904-6807; 70771-1496; 59762-5008; 68084-041; 63704-008; 24584-1051; 70710-1007; 63629-7929; 68245-0001; 70771-1497; 12634-502; 68084-040; 43386-160 |
| Synonyms |
Misoprostol | Novo-Misoprostol | Novo Misoprostol | SC-29333 | SC 29333 | SC29333 | SC-30249 | SC 30249 | SC30249 | Apo-Misoprostol | Apo Misoprostol | Misoprostol, (11beta,13E,16R)-Isomer | Glefos | Misoprostol, (11alpha,13E)-Isomer | Misoprostol, (11alpha,13E,16R)-Isomer | Misoprostol, (11alpha,13Z)-(+-)-Isomer | Misoprostol, (11alpha.13E,16S)-Isomer | Misoprostol, (11beta,13E)-(+-)-Isomer | Misoprostol, (11beta,13E,16S)-Isomer | Cytotec |
