Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Mianserin
Drug ID BADD_D01454
Description A tetracyclic compound with antidepressant effects. Mianserin was previously available internationally, however in most markets it has been phased out in favour of [mirtazapine].
Indications and Usage For the treatment of depression.
Marketing Status Not Available
ATC Code N06AX03
DrugBank ID DB06148
KEGG ID D08216
MeSH ID D008803
PubChem ID 4184
TTD Drug ID D0R6RO
NDC Product Code Not Available
Synonyms Mianserin | Mianserin Hydrochloride | Hydrochloride, Mianserin | Mianserin Monohydrochloride | Monohydrochloride, Mianserin | Tolvon | Lerivon | Org GB 94
Chemical Information
Molecular Formula C18H20N2
CAS Registry Number 24219-97-4
SMILES CN1CCN2C(C1)C3=CC=CC=C3CC4=CC=CC=C42
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Poisoning and toxicityCytochrome P450 2D6P10635T57392Not Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Agitation19.06.02.001; 17.02.05.012--
Agranulocytosis01.02.03.001--Not Available
Anaemia01.03.02.001--
Arthralgia15.01.02.001--
Arthritis15.01.01.001--
Asthenia08.01.01.001--Not Available
Bradycardia02.03.02.002--Not Available
Cardiac arrest02.03.04.001--
Cardiac failure02.05.01.001--
Confusional state19.13.01.001; 17.02.03.005--
Constipation07.02.02.001--
Dermatitis23.03.04.002--Not Available
Diplopia06.02.06.002; 17.17.01.005--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dry mouth07.06.01.002--
Ear disorder04.03.01.001--Not Available
Electrocardiogram QT prolonged13.14.05.004--
Eye disorder06.08.03.001--Not Available
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Gastrointestinal disorder07.11.01.001--Not Available
Gynaecomastia21.05.04.003; 05.05.02.003--
Headache17.14.01.001--
Hepatic function abnormal09.01.02.001--Not Available
Hepatitis09.01.07.004--Not Available
Hyperkinesia17.01.02.008--Not Available
Hypertension24.08.02.001--
Hypomania19.16.02.001--Not Available
Hypotension24.06.03.002--
Jaundice23.03.03.030; 09.01.01.004; 01.06.04.004--Not Available
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