Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Methoxsalen
Drug ID BADD_D01420
Description A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA adducts in the presence of ultraviolet A irradiation.
Indications and Usage For the treatment of psoriasis and vitiligo
Marketing Status approved
ATC Code D05AD02; D05BA02
DrugBank ID DB00553
KEGG ID D00139
MeSH ID D008730
PubChem ID 4114
TTD Drug ID D08SKH
NDC Product Code 62991-2896; 64067-216; 64380-752; 72643-011; 62350-0049
UNII U4VJ29L7BQ
Synonyms Methoxsalen | Xanthotoxin | 8-Methoxypsoralen | 8 Methoxypsoralen | Ammoidin | Deltasoralen | Dermox | Geroxalen | Meladinina | Methoxa-Dome | Methoxa Dome | Oxsoralen | Méladinine | Meladinine | Oxsoralen-Ultra | Oxsoralen Ultra | Puvalen | Ultramop | 8-MOP | 8 MOP | 8MOP | Meloxine
Chemical Information
Molecular Formula C12H8O4
CAS Registry Number 298-81-7
SMILES COC1=C2C(=CC3=C1OC=C3)C=CC(=O)O2
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Folliculitis23.11.04.003; 11.02.01.053--
Gastrointestinal disorder07.11.01.0010.000521%Not Available
Gastrointestinal haemorrhage07.12.02.001; 24.07.02.0090.001042%Not Available
Graft versus host disease12.02.09.001; 10.02.01.0270.001823%Not Available
Haemolysis01.06.04.0020.000521%
Headache17.14.01.001--
Herpes simplex23.11.05.004; 11.05.02.001--Not Available
Hypersensitivity10.01.03.003--
Hypertension24.08.02.0010.001042%
Hypocalcaemia14.04.01.0040.000781%
Hypotension24.06.03.0020.003125%
Hypovolaemia14.05.05.0020.000521%Not Available
Hypoxia22.02.02.0030.000521%
Infection11.01.08.002--Not Available
Insomnia19.02.01.002; 17.15.03.002--
Leukoderma23.05.02.001--Not Available
Loss of consciousness17.02.04.0040.000781%Not Available
Maculopathy06.09.03.0070.000781%Not Available
Malaise08.01.01.0030.002187%
Miliaria23.02.03.014--Not Available
Muscle haemorrhage15.05.03.017; 12.01.07.016; 24.07.01.0370.000521%Not Available
Muscle spasms15.05.03.004--
Myocardial infarction24.04.04.009; 02.02.02.0070.000521%
Nausea07.01.07.001--
Nervousness19.06.02.003--Not Available
Obliterative bronchiolitis22.03.01.012; 12.02.09.036; 10.02.01.0960.000521%Not Available
Oedema14.05.06.010; 08.01.07.0060.000781%Not Available
Pain of skin23.03.03.003--
Paraesthesia23.03.03.094; 17.02.06.0050.000521%
Pemphigoid10.04.02.002; 23.03.01.0040.000521%Not Available
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