Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Methoxsalen
Drug ID BADD_D01420
Description A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia. It is a photoactive substance that forms DNA adducts in the presence of ultraviolet A irradiation.
Indications and Usage For the treatment of psoriasis and vitiligo
Marketing Status Prescription; Discontinued
ATC Code D05AD02; D05BA02
DrugBank ID DB00553
KEGG ID D00139
MeSH ID D008730
PubChem ID 4114
TTD Drug ID D08SKH
NDC Product Code 51927-1685; 62350-0049; 62991-2896; 42249-1002; 64067-216; 64380-752; 51927-0162; 72643-011
Synonyms Methoxsalen | Xanthotoxin | 8-Methoxypsoralen | 8 Methoxypsoralen | Ammoidin | Deltasoralen | Dermox | Geroxalen | Meladinina | Methoxa-Dome | Methoxa Dome | Oxsoralen | Méladinine | Meladinine | Oxsoralen-Ultra | Oxsoralen Ultra | Puvalen | Ultramop | 8-MOP | 8 MOP | 8MOP | Meloxine
Chemical Information
Molecular Formula C12H8O4
CAS Registry Number 298-81-7
SMILES COC1=C2C(=CC3=C1OC=C3)C=CC(=O)O2
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Feeling abnormal08.01.09.014--Not Available
Folliculitis11.01.12.018; 23.09.04.007--
Gastrointestinal disorder07.11.01.0010.002057%Not Available
Gastrointestinal haemorrhage24.07.02.009; 07.12.02.0010.002057%Not Available
Graft versus host disease12.02.09.001; 10.02.01.0270.001341%Not Available
Haematocrit decreased13.01.05.0010.002057%Not Available
Haemoglobin decreased13.01.05.0030.003085%Not Available
Headache17.14.01.001--
Heart rate increased13.14.04.0020.002057%Not Available
Herpes simplex23.09.03.001; 11.05.02.001--Not Available
Hypersensitivity10.01.03.003--
Hypertension24.08.02.0010.003085%
Hypotension24.06.03.0020.007199%
Hypoxia22.02.02.0030.002057%
Infection11.01.08.0020.004292%Not Available
Insomnia19.02.01.002; 17.15.03.002--
Leukoderma23.05.02.001--Not Available
Maculopathy06.09.03.0070.002057%Not Available
Malaise08.01.01.0030.006170%
Miliaria23.02.03.014--Not Available
Muscle haemorrhage24.07.01.037; 15.05.03.0170.002057%Not Available
Muscle spasms15.05.03.004--
Nausea07.01.07.001--
Nervousness19.06.02.003--Not Available
Oedema14.05.06.010; 08.01.07.0060.003085%Not Available
Pain08.01.08.0040.004114%
Pain of skin23.03.03.003--
Photosensitivity reaction23.03.09.0030.003085%
Pneumonia22.07.01.003; 11.01.09.003--Not Available
Presyncope24.06.02.010; 17.02.05.009; 02.01.02.0070.003085%
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