Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Mercaptoethanesulfonic acid
Drug ID BADD_D01391
Description Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis.[A18572]
Indications and Usage Mesna is a uroprotective agent and is used prophylactically to reduce ifosfamide and cyclophosphamide induced hemorrhagic cystitis.[A18572]
Marketing Status approved; investigational
ATC Code R05CB05; V03AF01
DrugBank ID DB09110
KEGG ID D01459
MeSH ID D015080
PubChem ID 598
TTD Drug ID D0C3YQ
NDC Product Code Not Available
UNII VHD28S0H7F
Synonyms Mesna | Mesnum | Sodium 2-Mercaptoethanesulphonate | 2-Mercaptoethanesulphonate, Sodium | Ethanesulfonic acid, 2-mercapto-, monosodium salt | ASTA-D 7093 | ASTA D 7093 | ASTAD 7093 | Coenzyme M | MESNA-cell | MESNA cell | Mesnex | 2-Mercaptoethanesulfonate | 2 Mercaptoethanesulfonate | Mistabron | Mistabronco | Mucofluid | Mitexan | UCB-3983 | UCB 3983 | UCB3983 | Uromitexan | Ziken
Chemical Information
Molecular Formula C2H6O3S2
CAS Registry Number 3375-50-6
SMILES C(CS(=O)(=O)O)S
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Face oedema23.04.01.004; 10.01.05.002; 08.01.07.003--
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Flatulence07.01.04.002--
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
Gastrointestinal pain07.01.05.005--
Haematuria20.02.01.006; 21.10.01.018; 24.07.01.047--
Haemoptysis02.11.04.009; 24.07.01.006; 22.02.03.004--Not Available
Headache17.14.01.001--
Hepatitis09.01.07.004--Not Available
Hyperaesthesia23.03.03.080; 17.02.06.004--Not Available
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
Hypokalaemia14.05.03.002--
Hypotension24.06.03.002--
Influenza like illness08.01.03.010--
Injection site reaction12.07.03.015; 08.02.03.014--
Insomnia19.02.01.002; 17.15.03.002--
Leukopenia01.02.02.001--Not Available
Lymphadenopathy01.09.01.002--Not Available
Malaise08.01.01.003--
Myalgia15.05.02.001--
Nasal congestion22.04.04.001--
Nausea07.01.07.001--
Oedema14.05.06.010; 08.01.07.006--Not Available
Oedema peripheral14.05.06.011; 08.01.07.007; 02.05.04.007--
Pain08.01.08.004--
Pain in extremity15.03.04.010--
Pallor24.03.04.001; 23.03.03.031; 08.01.03.032--Not Available
The 2th Page    First    Pre   2 3    Next   Last    Total 3 Pages