Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ketorolac tromethamine
Drug ID BADD_D01233
Description Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution.[L6358][L6508][L11055][L3674][L11070] It's analgesic properties make it a useful pain management tool across many settings including postoperative pain, rheumatoid arthritis, osteoarthritis, menstrual disorders, headaches, spinal and soft tissue pain, and ankylosing spondylitis.[L6520] Impressively, ketorolac has a similar efficacy to standard doses of morphine and meperidine making it a useful opioid sparing agent.[L6511]
Indications and Usage For the short-term (~5 days) management of moderately severe acute pain that requires analgesia at the opioid level, usually in a postoperative setting.
Marketing Status Prescription; Discontinued
ATC Code M01AB15; S01BC05
DrugBank ID DB00465
KEGG ID D00813
MeSH ID D020911
PubChem ID 84003
TTD Drug ID Not Available
NDC Product Code 70518-2927; 0023-2181; 25021-700; 71205-582; 35356-696; 72611-719; 0404-9952; 60687-104; 0409-3796; 60505-1003; 0023-9277; 0338-0076; 71872-7212; 63278-1056; 68083-132; 51662-1488; 35573-450; 50090-2746; 0409-3795; 0404-9884; 50090-4635; 50090-5428; 71205-594; 63323-162; 70518-3308; 45865-613; 71872-7118; 70860-701; 70529-119; 0487-6232; 0404-9883; 50090-4583; 51655-170; 69344-144; 55154-0120; 63323-161; 71872-7234; 72266-119; 68788-8149; 0338-0072; 71872-7132; 61919-138; 66267-418; 63629-2488; 71872-7131; 65862-775; 55150-340; 50090-5013; 70529-121; 70529-120; 80425-0139; 60760-314; 12711-5990; 71872-7213; 62991-2818; 68083-103; 25021-701; 55154-1555; 66993-193; 50090-2762; 68083-134; 76420-250; 72189-335; 71872-7119; 0395-8216; 71872-7022; 43235-0001; 55289-328; 42571-137; 0641-6043; 68071-1787; 55154-9366; 52584-725; 64679-758; 0093-0314; 0641-6041; 55154-9368; 72611-725; 71205-116; 71335-1904; 17478-207; 55154-6960; 69543-388; 71872-7185; 70860-700; 68071-2576; 53069-0620; 14501-0010; 67296-1412; 0641-6042; 76045-107; 0338-0069; 50090-3397; 72189-054; 55154-1556; 68083-104; 72611-722; 68071-2443; 64679-757; 47335-221; 63187-628; 72266-118; 51662-1295; 0409-3793; 55150-341; 50090-3364; 70518-0048; 66267-832; 71872-7188; 51927-0111; 71335-1803; 76045-209; 53002-6990; 63187-128; 51552-1371; 53002-7780; 76420-032; 51927-3443; 76045-104; 70518-2610; 60758-773; 49452-3926; 66577-045; 55154-9398; 63629-2974; 49711-0103; 42291-358; 50090-5609; 0023-3507; 68071-4811; 61314-126; 50090-0601; 55150-339; 66022-0117; 70529-122; 43063-904; 65044-7424; 55111-014; 49452-3919; 76420-252; 71205-296; 68788-7517; 51662-1292; 68071-2400; 47335-219; 47335-220; 38779-2249; 52584-722; 70518-3369; 0378-1134; 66577-016; 68083-133; 68071-2569; 17478-209; 50090-3550; 52584-719; 63187-777; 76045-105; 76420-184; 65862-770; 17478-208; 68071-2252
Synonyms Ketorolac Tromethamine | Acular | Toradol
Chemical Information
Molecular Formula C19H24N2O6
CAS Registry Number 74103-07-4
SMILES C1CN2C(=CC=C2C(=O)C3=CC=CC=C3)C1C(=O)O.C(C(CO)(CO)N)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Paraesthesia17.02.06.005--
Paranoia19.05.01.005--Not Available
Peptic ulcer07.04.07.001--Not Available
Photophobia17.17.02.006; 06.01.01.004--
Photosensitivity reaction23.03.09.003--
Pneumonia22.07.01.003; 11.01.09.003--Not Available
Pollakiuria20.02.02.007--
Polyuria20.02.03.002--Not Available
Proteinuria20.02.01.011--
Pruritus23.03.12.001--
Pulmonary embolism22.06.02.001; 24.01.06.001--Not Available
Pulmonary oedema22.01.03.003; 02.05.02.003--
Pupillary disorder17.02.11.006; 06.05.03.008--Not Available
Purpura24.07.06.005; 23.06.01.004; 01.01.04.003--
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Rash maculo-papular23.03.13.004--
Rectal haemorrhage24.07.02.018; 07.12.03.001--
Renal failure20.01.03.005--Not Available
Respiratory depression22.02.01.010; 17.02.05.047--Not Available
Retinal haemorrhage24.07.05.003; 06.10.01.001--Not Available
Rhinitis22.07.03.006; 11.01.13.004--
Rhinorrhoea22.02.05.010--
Seizure17.12.03.001--
Sepsis11.01.11.003--
Shock24.06.02.002--Not Available
Skin disorder23.03.03.007--Not Available
Somnolence17.02.04.006; 19.02.05.003--
Speech disorder22.02.05.034; 19.19.02.002; 17.02.08.003--Not Available
Stevens-Johnson syndrome23.03.01.007; 12.03.01.014; 11.07.01.005; 10.01.03.020--
The 7th Page    First    Pre   7 8 9 10    Next   Last    Total 10 Pages