Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Iothalamic acid
Drug ID BADD_D01184
Description Iothalamic acid is an iodine containing organic anion used as a diagnostic contrast agent.
Indications and Usage Conray may also be used for enhancement of computed tomographic scans performed for detection and evaluation of lesions in the liver, pancreas, kidneys, abdominal aorta, mediastinum, abdominal cavity and retroperitoneal space.
Marketing Status Discontinued
ATC Code V08AA04
DrugBank ID DB09133
KEGG ID D01258
MeSH ID D007483
PubChem ID 3737
TTD Drug ID D02KCV
NDC Product Code 52134-0503
Synonyms Iothalamic Acid | Acid, Iothalamic | Methalamic Acid | Acid, Methalamic | Iotalamic Acid | Acid, Iotalamic | Conray 420 | Iodothalamate | Sodium Iothalamate | Iothalamate, Sodium | Iothalamic Acid, Monosodium Salt | Iothalamic Acid, Calcium (2:1) Salt | Iothalamic Acid, Monosilver (1+) Salt | Iothalamic Acid, Monosodium Salt, Dimer | Lopamidol | Angio-Conray | Angio Conray | AngioConray | Iothalamate
Chemical Information
Molecular Formula C11H9I3N2O4
CAS Registry Number 2276-90-6
SMILES CC(=O)NC1=C(C(=C(C(=C1I)C(=O)O)I)C(=O)NC)I
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hypertension24.08.02.001--
Hypoaesthesia17.02.06.023--Not Available
Hypotension24.06.03.002--
Infection11.01.08.002--Not Available
Injury12.01.08.004--Not Available
Laryngeal oedema23.04.01.005; 22.04.02.001; 10.01.05.003--
Laryngospasm22.04.02.002--
Loss of consciousness17.02.04.004--Not Available
Muscle spasms15.05.03.004--
Myelitis transverse17.06.02.002; 10.04.10.006--Not Available
Nasal congestion22.04.04.001--
Nausea07.01.07.001--
Necrosis24.04.02.006; 08.03.03.001--Not Available
Oedema14.05.06.010; 08.01.07.006--Not Available
Oliguria20.01.03.004--Not Available
Pain08.01.08.004--
Paraesthesia17.02.06.005--
Paralysis17.01.04.004--Not Available
Paresis17.01.04.008--Not Available
Pruritus23.03.12.001--
Pulmonary oedema22.01.03.003; 02.05.02.003--
Rash maculo-papular23.03.13.004--
Seizure17.12.03.001--
Sensory loss17.02.07.007--Not Available
Shock24.06.02.002--Not Available
Sneezing22.02.05.011--
Spinal cord injury17.10.04.001; 12.01.13.002--Not Available
Syncope24.06.02.012; 17.02.04.008; 02.01.02.008--
Thrombophlebitis24.01.02.001--Not Available
Thrombosis24.01.01.006--Not Available
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