Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Interferon alfa-2b
Drug ID BADD_D01167
Description Interferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). A type I interferon consisting of 165 amino acid residues with arginine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent.
Indications and Usage For the treatment of hairy cell leukemia, malignant melanoma, and AIDS-related Kaposi's sarcoma.
Marketing Status approved
ATC Code L03AB05
DrugBank ID DB00105
KEGG ID D02745
MeSH ID D000077190
PubChem ID 71306834
TTD Drug ID D0P0WV
NDC Product Code 53713-0079; 0085-1168; 53713-0078; 53713-0081; 0085-4351; 0085-4352; 53713-0082; 53713-0080; 0085-1133; 0085-4350
UNII 43K1W2T1M6
Synonyms Interferon alpha-2 | Interferon alpha 2 | Interferon-alpha 2 | Interferon alpha-A | Interferon alpha A | LeIF A | IFN-alpha 2 | IFN-alpha-2 | Interferon alfa-2a | Interferon alfa 2a | Recombinant Interferon alpha-2a | Interferon alpha-2a, Recombinant | Recombinant Interferon alpha 2a | Roferon-A | Roferon A | RoferonA | Ro 22-8181 | Ro 22 8181 | Ro 228181 | Viferon | Sch-30500 | Sch 30500 | Sch30500 | Intron A (Interferon) | Reaferon | Interferon alfa-2b | Interferon alfa 2b | Interferon alpha-2b, Recombinant | Interferon alpha 2b, Recombinant | Recombinant Interferon alpha-2b | Recombinant Interferon alpha 2b | IFNalpha-2b, Recombinant | IFNalpha 2b, Recombinant | Recombinant IFNalpha-2b
Chemical Information
Molecular Formula C16H17Cl3I2N3NaO5S
CAS Registry Number 98530-12-2
SMILES CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)N2C=CN=C2.C(S(=O)(=O)[O-])(I)I.[Na+]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Tendonitis15.07.01.003; 12.01.07.007--Not Available
Tension19.06.02.005--Not Available
Testicular pain21.13.01.005--
Thinking abnormal19.10.03.001; 17.02.05.023--Not Available
Thirst14.03.02.007; 08.01.09.021--Not Available
Thrombocytopenia01.08.01.002--Not Available
Thrombocytopenic purpura01.08.01.003; 23.06.01.007--Not Available
Thrombophlebitis24.01.02.001--Not Available
Thrombosis24.01.01.006--Not Available
Thrombotic thrombocytopenic purpura24.07.06.014; 23.06.01.011; 01.08.01.005--
Thyroid disorder05.02.01.002--Not Available
Tinnitus04.04.01.002; 17.04.07.004--
Tongue discolouration07.14.02.006--Not Available
Tongue disorder07.14.01.002--Not Available
Tonsillitis22.07.03.008; 11.01.13.006--Not Available
Tooth abscess11.01.04.003; 07.09.01.003--Not Available
Tooth disorder07.09.05.001--Not Available
Toothache07.09.06.001--
Toxic epidermal necrolysis10.01.01.006; 23.03.01.008; 12.03.01.015; 11.07.01.006--
Tracheitis22.07.03.009; 11.01.13.007--
Transient ischaemic attack24.04.06.005; 17.08.04.001--
Transplant rejection12.02.05.022; 10.02.03.002--Not Available
Tremor17.01.06.002--
Trichomoniasis11.06.05.002--Not Available
Upper respiratory tract infection22.07.03.011; 11.01.13.009--
Urethral disorder20.07.01.002--Not Available
Urinary incontinence20.02.02.010; 17.05.01.008--
Urinary tract disorder20.08.01.001--Not Available
Urinary tract infection20.08.02.001; 11.01.14.004--
Urticaria23.04.02.001; 10.01.06.001--
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