Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Glatiramer
Drug ID BADD_D01020
Description Glatiramer acetate consists of the acetate salts of synthetic polypeptides, containing four naturally occurring amino acids: L-glutamic acid, L-alanine, L-tyrosine, and L-lysine with an average molar fraction of 0.141, 0.427, 0.095, and 0.338, respectively. The average molecular weight of glatiramer acetate is 5,000-9,000 daltons. It is an immunomodulator, licensed in much of the world for reduced frequency of relapses in relapsing-remitting multiple sclerosis.
Indications and Usage For reduction of the frequency of relapses in patients with Relapsing-Remitting Multiple Sclerosis.
Marketing Status approved; investigational
ATC Code L03AX13
DrugBank ID DB05259
KEGG ID D04318
MeSH ID D000068717
PubChem ID 65370
TTD Drug ID D04CRL
NDC Product Code 0378-6961; 41524-0004
UNII U782C039QP
Synonyms Glatiramer Acetate | Acetate, Glatiramer | Copaxone | Glatiramer | TV 5010 | 5010, TV | TV5010 | TV-5010
Chemical Information
Molecular Formula C23H41N5O11
CAS Registry Number 28704-27-0
SMILES CC(C(=O)O)N.C1=CC(=CC=C1CC(C(=O)O)N)O.C(CCN)CC(C(=O)O)N.C(CC(=O)O)C(C(=O)O)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Breast engorgement21.05.05.002; 18.08.02.001--Not Available
Breast enlargement21.05.04.001--Not Available
Bronchitis22.07.01.001; 11.01.09.001--
Burning sensation08.01.09.029; 17.02.06.001--Not Available
Bursitis15.04.01.001; 12.04.03.010--Not Available
Cardiac failure congestive02.05.01.002--Not Available
Cardiac murmur13.14.01.001--Not Available
Cardiomegaly02.04.02.001--Not Available
Cardiomyopathy02.04.01.001--Not Available
Cataract06.06.01.001--
Cellulitis23.11.02.004; 11.02.01.001--Not Available
Central nervous system neoplasm17.20.01.001; 16.30.01.001--Not Available
Cerebrovascular accident24.03.05.001; 17.08.01.007--
Cervical dysplasia21.06.01.002--Not Available
Chest pain22.12.02.003; 08.01.08.002; 02.02.02.011--Not Available
Chills15.05.03.016; 08.01.09.001--
Cholecystitis09.03.01.001--
Cholelithiasis09.03.01.002--Not Available
Colitis07.08.01.001--
Coma17.02.09.001--Not Available
Coronary artery occlusion12.02.01.036; 24.04.04.013; 02.02.01.006--Not Available
Cough22.02.03.001--
Cushing's syndrome24.08.04.001; 19.07.03.002; 14.11.01.007; 05.01.01.001--Not Available
Cushingoid24.08.02.004; 19.07.03.001; 14.11.01.006; 05.01.01.002--
Cyanosis23.06.04.005; 02.11.04.004; 24.03.01.007; 22.02.02.007--
Cyst16.02.02.002; 08.03.05.001--Not Available
Dental caries07.09.01.001--
Depressed level of consciousness17.02.04.002--
Dermatitis23.03.04.002--Not Available
Dermatitis bullous23.03.01.002--
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