Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Fluticasone furoate
Drug ID BADD_D00946
Description Fluticasone furoate is a synthetic glucocorticoid available as an inhaler and nasal spray for various inflammatory indications[FDA Label][F4364]. Fluticasone furoate was first approved in 2007[L5965].
Indications and Usage Breo Ellipta, a mixture of fluticasone furoate and vilanterol is indicated for the long-term, once-daily maintenance treatment of airflow obstruction in patients with COPD, including chronic bronchitis and emphysema. It is also indicated for once-daily maintenance treatment of asthma in patients aged 18 or older with reversible obstructive airways disease. Breo Ellipta should not be used for the relief of acute symptoms of asthma or COPD.
Marketing Status Prescription; OTC
ATC Code D07AC17; R01AD08; R01AD12; R03BA05; R03BA09
DrugBank ID DB08906
KEGG ID D06315
MeSH ID C523187
PubChem ID 9854489
TTD Drug ID D0Y7JU
NDC Product Code 63379-083; 59057-009; 52482-008; 47848-057; 0173-0876; 64918-1915; 55018-302; 0135-0616; 64918-1916; 0135-0615; 15308-2021; 58175-0553; 0173-0874; 59057-010; 63379-084; 49076-6451; 64918-1117; 22552-0042; 0173-0888; 63592-3370; 49076-6452; 64918-1910
Synonyms fluticasone furoate
Chemical Information
Molecular Formula C27H29F3O6S
CAS Registry Number 397864-44-7
SMILES CC1CC2C3CC(C4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)SCF)OC(=O)C5=CC=CO5)C)O)F)C)F
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Eye disorder06.08.03.001--Not Available
Gait disturbance17.02.05.016; 08.01.02.0020.004171%
Glaucoma06.03.01.002--
Headache17.14.01.001--
Herpes simplex23.09.03.001; 11.05.02.001--Not Available
Hyperkinesia17.01.02.008--Not Available
Hypersensitivity10.01.03.003--
Hypertension24.08.02.0010.002780%
Hypertensive crisis24.08.01.0010.002780%Not Available
Immune system disorder10.02.01.001--Not Available
Impaired healing08.03.02.001--Not Available
Infection11.01.08.002--Not Available
Intraocular pressure increased13.07.04.002--Not Available
Laryngeal pain22.02.05.036--
Menorrhagia21.01.03.002--
Migraine24.03.05.003; 17.14.02.001--Not Available
Myalgia15.05.02.0010.005561%
Myopathy15.05.05.0010.005561%Not Available
Nasal dryness22.04.03.002--Not Available
Nasal polyps22.04.03.010; 16.38.01.001--Not Available
Nasal septum perforation22.04.03.003--Not Available
Nasal septum ulceration22.04.03.016--Not Available
Nasopharyngitis22.07.03.002; 11.01.13.002--Not Available
Nausea07.01.07.0010.002780%
Nervous system disorder17.02.10.001--Not Available
Palpitations02.01.02.003--
Pharyngitis07.05.07.004; 11.01.13.003; 22.07.03.004--
Pneumonia22.07.01.003; 11.01.09.0030.004171%Not Available
Pyrexia08.05.02.003--
Rash23.03.13.0010.002780%Not Available
The 2th Page    First    Pre   2 3    Next   Last    Total 3 Pages