Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Fluorometholone acetate
Drug ID BADD_D00930
Description A glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p732)
Indications and Usage For the ophthalmic treatment of corticosteroid-responsive inflammation of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe.
Marketing Status Prescription; Discontinued
ATC Code C05AA06; D07AB06; D07XB04; D10AA01; S01BA07; S01CB05
DrugBank ID DB00324
KEGG ID D04221
MeSH ID D005469
PubChem ID 240767
TTD Drug ID D0P0HT
NDC Product Code 71776-100
Synonyms Fluorometholone | FML Liquifilm | PMS-Fluorometholone | PMS Fluorometholone | Cortisdin | Efflumidex | FML Forte | Flucon | Isopto Flucon | Flucon, Isopto | Fluor-Op | Fluor Op | Fluoro-Ophtal | Fluoro Ophtal | Fluoropos | FML
Chemical Information
Molecular Formula C24H31FO5
CAS Registry Number 3801-06-7
SMILES CC1CC2C3CCC(C3(CC(C2(C4(C1=CC(=O)C=C4)C)F)O)C)(C(=O)C)OC(=O)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Cataract06.06.01.001--
Glaucoma06.03.01.002--
Optic nerve injury17.04.05.008; 12.01.16.001; 06.11.02.001--Not Available
Visual acuity reduced17.17.01.011; 06.02.03.001--
Visual field defect17.17.01.001; 06.02.07.003--Not Available
Open globe injury06.11.01.008; 12.01.04.016--Not Available
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