Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Fenoprofen
Drug ID BADD_D00877
Description An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.
Indications and Usage For relief of the signs and symptoms of rheumatoid arthritis and osteoarthritis. Also for the relief of mild to moderate pain.
Marketing Status approved
ATC Code M01AE04
DrugBank ID DB00573
KEGG ID D02350
MeSH ID D005279
PubChem ID 3342
TTD Drug ID D03XYW
NDC Product Code Not Available
UNII RA33EAC7KY
Synonyms Fenoprofen | Fenoprofen Dihydrate, Calcium Salt | Nalgesic | Fenoprofen Calcium | Fenoprofen, Anhydrous, Calcium Salt | Nalfon
Chemical Information
Molecular Formula C15H14O3
CAS Registry Number 29679-58-1
SMILES CC(C1=CC(=CC=C1)OC2=CC=CC=C2)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Oliguria20.01.03.004--Not Available
Optic neuritis10.02.01.097; 17.04.05.001; 06.04.08.002--Not Available
Palpitations02.11.04.012--
Pancreatitis07.18.01.001--
Pancytopenia01.03.03.003--Not Available
Peptic ulcer07.04.07.001--Not Available
Personality change19.05.01.006; 17.02.05.019--
Pruritus23.03.12.001--
Pulmonary oedema22.01.03.003; 02.05.02.003--
Purpura23.06.01.004; 01.01.04.003; 24.07.06.005--
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Renal failure20.01.03.005--Not Available
Renal papillary necrosis20.01.07.002; 14.07.02.001; 05.07.02.001--Not Available
Seizure17.12.03.001--
Somnolence17.02.04.006; 19.02.05.003--
Stevens-Johnson syndrome10.01.01.045; 23.03.01.007; 12.03.01.014; 11.07.01.005--
Supraventricular tachycardia02.03.03.012--
Tachycardia02.03.02.007--Not Available
Tension19.06.02.005--Not Available
Thrombocytopenia01.08.01.002--Not Available
Tinnitus17.04.07.004; 04.04.01.002--
Toxic epidermal necrolysis23.03.01.008; 12.03.01.015; 11.07.01.006; 10.01.01.006--
Tremor17.01.06.002--
Trigeminal neuralgia17.04.08.001--Not Available
Upper respiratory tract infection22.07.03.011; 11.01.13.009--
Urticaria23.04.02.001; 10.01.06.001--
Vascular purpura23.06.01.008; 01.01.04.007; 24.07.06.011--Not Available
Vision blurred17.17.01.010; 06.02.06.007--
Vomiting07.01.07.003--
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ADReCS-Target
Drug Name ADR Term Target
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