Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ethosuximide
Drug ID BADD_D00846
Description An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.
Indications and Usage For the treatment of petit mal epilepsy.
Marketing Status approved
ATC Code N03AD01
DrugBank ID DB00593
KEGG ID D00539
MeSH ID D005013
PubChem ID 3291
TTD Drug ID D0Q4XQ
NDC Product Code 65655-0001; 0071-2418; 61748-025; 49452-2803; 0121-0670; 17349-0006; 59762-2250; 63629-8005; 59762-2350; 23155-532; 0071-0237; 42806-708; 64380-878; 69452-152; 11014-0047; 51927-3436; 42806-711; 10888-8169
UNII 5SEH9X1D1D
Synonyms Ethosuximide | Ethosuccimid | Ethylmethylsuccimide | Ethymal | Zarontin | Petnidan | Pyknolepsinum | Suksilep | Suxilep | Emeside | Etosuximida Faes | Faes, Etosuximida
Chemical Information
Molecular Formula C7H11NO2
CAS Registry Number 77-67-8
SMILES CCC1(CC(=O)NC1=O)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Euphoric mood19.04.02.006--
Eye disorder06.08.03.001--Not Available
Fatigue08.01.01.002--
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal pain07.01.05.005--
Generalised tonic-clonic seizure17.12.01.0020.004226%Not Available
Gingival hypertrophy07.09.13.008--Not Available
Haematuria21.10.01.018; 24.07.01.047; 20.02.01.006--
Hallucination, visual19.10.04.0070.004226%Not Available
Headache17.14.01.001--
Hepatomegaly09.01.05.0010.004226%Not Available
Hiccups07.01.06.009; 22.12.01.001--
Hirsutism23.02.04.001; 05.05.01.005--
Hyperkinesia17.01.02.008--Not Available
Hypersensitivity10.01.03.003--
Hypotension24.06.03.0020.004226%
Immune system disorder10.02.01.001--Not Available
Irritability19.04.02.013; 08.01.03.011--
Lethargy19.04.04.004; 17.02.04.003; 08.01.01.0080.004226%
Leukopenia01.02.02.001--Not Available
Libido increased19.08.03.002; 21.03.02.007--
Lymphadenopathy01.09.01.0020.008452%Not Available
Mental disability26.01.01.001--Not Available
Mental impairment19.21.02.003; 17.03.03.002--Not Available
Movement disorder17.01.02.0100.004226%Not Available
Muscle rigidity17.05.02.005; 15.05.04.0010.004226%Not Available
Muscle spasms15.05.03.004--
Myopia06.02.04.002--Not Available
Nausea07.01.07.0010.017748%
Nervous system disorder17.02.10.001--Not Available
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