Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Esterified estrogens
Drug ID BADD_D00820
Description Esterified estrogens contain a mixture of estrogenic substances; the principle component is estrone. Preparations contain 75% to 85% sodium estrone sulfate and 6% to 15% sodium equilin sulfate such that the total is not <90%. Esterified estrogens are a man-made mixture of estrogens that are used to treat symptoms of menopause such as hot flashes, vaginal dryness, vaginal burning or irritation, or other hormonal changes in the vagina. It is being also for the prevention and treatment of osteoporosis.
Indications and Usage It is also indicated for the treatment of menopausal symptoms.
Marketing Status Not Available
ATC Code Not Available
DrugBank ID DB09381
KEGG ID Not Available
MeSH ID D042724
PubChem ID Not Available
TTD Drug ID Not Available
NDC Product Code 61570-072; 61570-073; 61570-075; 61570-074
Synonyms Estrogens, Esterified (USP) | Esterified Estrogens (USP)
Chemical Information
Molecular Formula Not Available
CAS Registry Number
SMILES Not Available
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Gallbladder disorder09.03.02.001--Not Available
Haemangioma24.03.06.004; 16.02.01.002--Not Available
Haemorrhagic disorder24.07.01.021; 01.01.03.004--Not Available
Headache17.14.01.001--
Hirsutism23.02.04.001; 05.05.01.005--
Hypocalcaemia14.04.01.004--
Irritability19.04.02.013; 08.01.03.011--
Jaundice cholestatic09.01.01.005--Not Available
Metrorrhagia21.01.01.006--Not Available
Migraine24.03.05.003; 17.14.02.001--Not Available
Mood altered19.04.02.007--Not Available
Muscle spasms15.05.03.004--
Myocardial infarction24.04.04.009; 02.02.02.007--
Nausea07.01.07.001--
Nervousness19.06.02.003--Not Available
Oedema08.01.07.006; 14.05.06.010--Not Available
Ovarian cancer21.11.01.003; 16.12.04.001--Not Available
Pain08.01.08.004--
Pancreatitis07.18.01.001--
Porphyria14.14.01.001; 03.08.01.001--Not Available
Premenstrual syndrome19.04.02.009; 21.01.01.007--Not Available
Pruritus23.03.12.001--
Pulmonary embolism24.01.06.001; 22.06.02.001--Not Available
Rash23.03.13.001--Not Available
Tenderness08.01.08.005--Not Available
Thrombophlebitis24.01.02.001--Not Available
Thrombophlebitis superficial24.01.02.002--
Urticaria23.04.02.001; 10.01.06.001--
Uterine leiomyoma21.07.02.004; 16.04.02.001--Not Available
Vaginal haemorrhage24.07.03.005; 21.08.01.001--
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