Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Dicloxacillin sodium
Drug ID BADD_D00658
Description One of the penicillins which is resistant to penicillinase.
Indications and Usage Used to treat infections caused by penicillinase-producing staphylococci which have demonstrated susceptibility to the drug.
Marketing Status Prescription; Discontinued
ATC Code J01CF01
DrugBank ID DB00485
KEGG ID D02137
MeSH ID D004009
PubChem ID 23667628
TTD Drug ID D0R2KJ
NDC Product Code 43063-473; 43063-180; 66267-073; 67296-1205; 65862-278; 55289-592; 0781-2248; 50090-0310; 0093-3125; 0093-3123; 0781-2258; 76420-183
Synonyms Dicloxacillin | Dicloxacycline | Dichloroxacillin | Dicloxaciclin | Diclocil | Dicloxacillin Sodium | Sodium, Dicloxacillin | Dicloxacillin, Monosodium Salt, Mono-Hydrate | Dicloxacillin, Monosodium Salt, Anhydrous | Dicloxsig | Distaph | Dycill | Dynapen | InfectoStaph | Pathocil | Posipen | Cilpen | Ditterolina
Chemical Information
Molecular Formula C19H16Cl2N3NaO5S
CAS Registry Number 343-55-5
SMILES CC1=C(C(=NO1)C2=C(C=CC=C2Cl)Cl)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)[O-].[Na+]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Infusion site phlebitisIntercellular adhesion molecule 1P05362T26203Not Available
Injection site abscessIntercellular adhesion molecule 1P05362T26203Not Available
Injection site atrophyIntercellular adhesion molecule 1P05362T26203Not Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Agranulocytosis01.02.03.001--Not Available
Angioedema23.04.01.001; 10.01.05.009--Not Available
Arthralgia15.01.02.001--
Aspartate aminotransferase increased13.03.01.006--
Bronchospasm22.03.01.004; 10.01.03.012--
Circulatory collapse24.06.02.001--Not Available
Death08.04.01.001--
Diarrhoea07.02.01.001--
Eosinophilia01.02.04.001--
Haematuria24.07.01.047; 20.02.01.006--
Hepatotoxicity12.03.01.008; 09.01.07.009--Not Available
Hypotension24.06.03.002--
Laryngeal oedema23.04.01.005; 22.04.02.001; 10.01.05.003--
Laryngospasm22.04.02.002--
Malaise08.01.01.003--
Myalgia15.05.02.001--
Nausea07.01.07.001--
Neurotoxicity17.02.10.002; 12.03.01.011--Not Available
Neutropenia01.02.03.004--Not Available
Proteinuria20.02.01.011--
Pruritus23.03.12.001--
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Renal failure20.01.03.005--Not Available
Stomatitis07.05.06.005--
Tongue discolouration07.14.02.006--Not Available
Urticaria23.04.02.001; 10.01.06.001--
Vomiting07.01.07.003--
Tubulointerstitial nephritis20.05.02.002--Not Available
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