Drug Name |
Dexamethasone sodium phosphate |
Drug ID |
BADD_D00625 |
Description |
Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and other conditions.[L10701] Developed in 1957, it is structurally similar to other corticosteroids like [hydrocortisone] and [prednisolone].[A188724]
Dexamethasone was granted FDA approval on 30 October 1958.[L10695] In a press release for the Randomized Evaluation of COVID-19 Therapy (RECOVERY) trial on 16 June 2020, dexamethasone was recommended for use in COVID-19 patients with severe respiratory symptoms. Dexamethasone reduced deaths by approximately one third in patients requiring ventilation and by one fifth in those requiring oxygen.[L14318] |
Indications and Usage |
Intranasal aerosol: for the treatment of allergic ot inflammatory nasal conditions, and nasal polyps |
Marketing Status |
Prescription; Discontinued |
ATC Code |
A01AC02; C05AA09; D07AB19; D07XB05; D10AA03; H02AB02; R01AD03; S01BA01; S01CB01; S02BA06; S03BA01 |
DrugBank ID |
DB01234
|
KEGG ID |
D00975
|
MeSH ID |
C004180
|
PubChem ID |
16961
|
TTD Drug ID |
D0NA8U
|
NDC Product Code |
67457-423; 68083-474; 67457-418; 0404-9841; 71872-7205; 68083-473; 52584-239; 70121-1452; 50090-0627; 60722-3014; 0641-6145; 70069-025; 51662-1432; 72572-122; 53225-3660; 71872-7147; 51927-0135; 71872-7021; 71872-7128; 0641-6146; 67457-484; 24208-720; 71872-7157; 70529-118; 71872-7092; 55150-304; 0404-9843; 50090-3541; 52584-421; 67457-421; 70518-3379; 51662-1391; 55150-305; 70069-024; 63323-506; 51662-1370; 49452-2473; 50090-3300; 55150-239; 70121-1451; 55150-238; 76420-077; 0395-8141; 67457-420; 71872-7171; 51662-1343; 24002-0025; 70069-022; 55154-9364; 55150-237; 67457-483; 71872-7164; 70121-1450; 67457-419; 72572-120; 71872-7091; 71872-7153; 79572-013; 52128-159; 70518-2936; 52584-420; 0641-0367; 63323-165; 50090-2313; 52584-422; 50090-4567; 70069-023; 71872-7239; 76420-185; 51927-1430; 65089-0001; 55154-8338; 0404-9842; 70518-3119; 67457-422; 0009-5027; 76045-106; 76045-109; 51662-1297; 70518-3019; 51552-0025; 76420-270; 70529-112; 38779-0071; 76045-210; 55154-5118; 70518-0532; 81565-202; 49452-2470; 57582-015; 70529-045; 63323-516; 70518-0410; 70121-1399; 70069-021; 82298-113 |
Synonyms |
dexamethasone 21-phosphate | dexamethasone phosphate | dexamethasone 21-phosphate, monosodium salt, (11beta,16alpha)-isomer | dexamethasone sodium phosphate | dexamethasonedisodium phosphate | dexamethasone phosphate disodium salt | Solu- Decadron | Spersadex | Spersadox | dexamethasone 21-phosphate, (6alpha,11beta,16alpha)-isomer | dexamethasone 21-phosphate, disodium salt, (11beta,16alpha)-isomer | dexamethasone 21-phosphate, disodium salt, (6alpha,11beta,16alpha)-isomer | Decadron phosphate | dexamethasone 21-phosphate, sodium salt, (11beta,16alpha)-isomer | dexamethasone 21-phosphate, copper (+2) salt (2:3), (11beta,16alpha)-isomer |