Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Darbepoetin alfa
Drug ID BADD_D00583
Description Human erythropoietin with 2 aa substitutions to enhance glycosylation (5 N-linked chains), 165 residues (MW=37 kD). Produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology.
Indications and Usage For the treatment of anemia (from renal transplants or certain HIV treatment)
Marketing Status approved; investigational
ATC Code B03XA02
DrugBank ID DB00012
KEGG ID D03651
MeSH ID D000068256
PubChem ID Not Available
TTD Drug ID D02LVZ
NDC Product Code 55513-004; 55513-032; 55513-111; 55513-021; 55513-023; 55513-005; 55513-006; 55513-025; 55513-028; 55513-110; 55513-057; 55513-003; 55513-002; 55513-027; 55513-098
UNII 15UQ94PT4P
Synonyms Darbepoetin alfa | Novel Erythropoiesis Stimulating Protein | NESP | Darbepoietin alfa | Aranesp | Aranest | KRN 321 | KRN321 | KRN-321
Chemical Information
Molecular Formula Not Available
CAS Registry Number 209810-58-2
SMILES Not Available
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Angina pectoris24.04.04.002; 02.02.02.002--
Aplasia pure red cell10.02.01.003; 01.03.03.001--Not Available
Cerebrovascular accident17.08.01.007; 24.03.05.001--
Cerebrovascular disorder24.03.05.002; 17.08.02.002--Not Available
Cough22.02.03.001--
Death08.04.01.001--
Dyspnoea02.11.05.003; 22.02.01.004--
Embolism arterial24.01.01.014--
Embolism venous24.01.01.003--Not Available
Erythema23.03.06.001--Not Available
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
Hypervolaemia02.05.04.019; 14.05.06.003--Not Available
Injection site pain08.02.03.010; 12.07.03.011--Not Available
Myocardial infarction24.04.04.009; 02.02.02.007--
Oedema14.05.06.010; 08.01.07.006--Not Available
Oedema peripheral14.05.06.011; 08.01.07.007; 02.05.04.007--
Pulmonary embolism24.01.06.001; 22.06.02.001--Not Available
Rash23.03.13.001--Not Available
Seizure17.12.03.001--
Thrombocytopenia01.08.01.002--Not Available
Arteriovenous graft thrombosis24.01.01.026; 12.02.01.012--Not Available
Embolism24.01.01.009--
Neoplasm progression16.16.02.005--Not Available
Vascular access complication12.02.01.007; 08.07.05.010--
Procedural hypotension24.06.03.010; 12.02.05.026--Not Available
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