Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Clomiphene
Drug ID BADD_D00497
Description A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue.
Indications and Usage Used mainly in female infertility due to anovulation (e.g. due to polycystic ovary syndrome) to induce ovulation.
Marketing Status approved; investigational
ATC Code G03GB02
DrugBank ID DB00882
KEGG ID D07726
MeSH ID D002996
PubChem ID 1548953
TTD Drug ID D0CT9Y
NDC Product Code Not Available
UNII 1HRS458QU2
Synonyms Clomiphene | Clomifene | Chloramiphene | Clomifen | Clomiphene Citrate | Citrate, Clomiphene | Clomiphene Hydrochloride | Hydrochloride, Clomiphene | Serophene | Gravosan | Klostilbegit | Clostilbegit | Clomid | Clomide | Dyneric
Chemical Information
Molecular Formula C26H28ClNO
CAS Registry Number 15690-57-0
SMILES CCN(CC)CCOC1=CC=C(C=C1)C(=C(C2=CC=CC=C2)Cl)C3=CC=CC=C3
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Palpitations02.11.04.012--
Pancreatitis07.18.01.001--
Paraesthesia23.03.03.094; 17.02.06.005--
Patent ductus arteriosus24.03.03.002; 03.07.01.001; 02.08.01.001--Not Available
Pectus excavatum22.09.01.003; 15.11.10.002; 03.11.10.002--Not Available
Phlebitis24.12.03.004; 12.02.01.002--
Photophobia17.17.02.006; 06.01.01.004--
Photopsia17.17.01.006; 06.02.06.004--
Pituitary tumour16.24.01.003; 05.03.05.002--Not Available
Plasma cell myeloma16.23.02.004; 01.14.02.004--Not Available
Plasmacytoma16.23.02.002; 01.14.02.002--Not Available
Pollakiuria20.02.02.007--
Polydactyly03.11.07.010; 15.11.07.010--Not Available
Pruritus23.03.12.001--
Pulmonary embolism24.01.06.001; 22.06.02.001--Not Available
Rash23.03.13.001--Not Available
Renal failure20.01.03.005--Not Available
Retinal haemorrhage24.07.05.003; 06.10.01.001--Not Available
Seizure17.12.03.001--
Shock24.06.02.002--Not Available
Spina bifida occulta03.10.02.007; 17.19.01.007--Not Available
Stillbirth18.01.02.002; 08.04.01.006--Not Available
Syncope02.11.04.015; 24.06.02.012; 17.02.04.008--
Syndactyly15.11.07.015; 03.11.07.015--Not Available
Tachycardia02.03.02.007--Not Available
Talipes15.11.07.007; 03.11.07.007--Not Available
Tenderness08.01.08.005--Not Available
Tension19.06.02.005--Not Available
Thrombophlebitis24.01.02.001--Not Available
Thrombosis24.01.01.006--Not Available
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