Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Syndactyly
ADR ID BADD_A04221
ADR Hierarchy
03      Congenital, familial and genetic disorders
03.11      Musculoskeletal and connective tissue disorders congenital
03.11.07      Musculoskeletal and connective tissue disorders of limbs congenital
03.11.07.015      Syndactyly
15      Musculoskeletal and connective tissue disorders
15.11      Musculoskeletal and connective tissue disorders congenital
15.11.07      Musculoskeletal and connective tissue disorders of limbs congenital
15.11.07.015      Syndactyly
Description A congenital anomaly of the hand or foot, marked by the webbing between adjacent fingers or toes. Syndactylies are classified as complete or incomplete by the degree of joining. Syndactylies can also be simple or complex. Simple syndactyly indicates joining of only skin or soft tissue; complex syndactyly marks joining of bony elements. [MeSH]
MedDRA Code 10042778
MeSH ID D013576; D013576; D013576
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Fingers webbed | Fusion of 2nd & 3rd toes both sides | Syndactyly | Syndactyly of fingers with fusion of bone | Syndactyly of fingers without fusion of bone | Syndactyly of multiple and unspecified sites | Syndactyly of toes with fusion of bone | Syndactyly of toes without fusion of bone | Toes webbed | Web bad fingers | Webbed fingers | Webbing & fusion 2-4th fingers L hand | Polysyndactyly | Syndactylies | Syndactylia | Syndactylias
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00306Budesonide0.000609%
BADD_D00378Cefaclor0.000213%
BADD_D00475Citalopram0.000292%
BADD_D00497Clomiphene--
BADD_D00912Fluconazole0.000206%
BADD_D00932Fluoxetine0.000272%
BADD_D01213Isotretinoin0.001263%
BADD_D01243Lamotrigine0.000387%
BADD_D01265Levetiracetam0.001143%
BADD_D01353Mebendazole0.024051%
BADD_D01418Methotrexate0.000840%
BADD_D01564Nicotine0.002552%
BADD_D01617Ondansetron0.000200%
BADD_D01627Oseltamivir0.000145%
BADD_D01679Paroxetine0.000280%
BADD_D01888Quetiapine0.000382%
BADD_D02010Sertraline0.000091%
BADD_D02329Valproic acid0.001550%
BADD_D02394Zolpidem0.000109%
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