| Drug Name |
Carvedilol phosphate |
| Drug ID |
BADD_D00375 |
| Description |
Carvedilol is a racemic mixture where the S(-) enantiomer is a beta adrenoceptor blocker and the R(+) enantiomer is both a beta and alpha-1 adrenoceptor blocker.[L7889,L7892] It is currently used to treat heart failure, left ventricular dysfunction, and hypertension.[L7889,L7892] The dual action of carvedilol is advantageous in combination therapies as moderate doses of 2 drugs have a decreased incidence of adverse effects compared to high dose monotherapy in the treatment of moderate hypertension.[A182306]
Carvedilol was granted FDA approval on 14 September 1995.[L7889] |
| Indications and Usage |
For the treatment of mild or moderate (NYHA class II or III) heart failure of ischemic or cardiomyopathic origin. |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
C07AG02 |
| DrugBank ID |
DB01136
|
| KEGG ID |
D03415
|
| MeSH ID |
D000077261
|
| PubChem ID |
9827459
|
| TTD Drug ID |
D0W9LX
|
| NDC Product Code |
69784-713; 72761-003; 60505-4715; 51407-052; 12658-0590; 0007-3371; 60505-4714; 61187-004; 0007-3387; 60505-3678; 60505-4713; 57664-665; 0007-3370; 65015-884; 57664-666; 60505-3679; 16714-229; 60505-3680; 16714-227; 0007-3385; 0007-3388; 69784-716; 36974-0067; 63629-8794; 51407-053; 16714-228; 69784-714; 51407-051; 60505-4716; 0007-3383; 60505-3681; 53873-061; 63415-0127; 16714-230; 51407-050; 53873-060; 53873-062; 53873-063; 69784-715; 0007-3372; 57664-663; 0007-3373; 57664-664 |
| Synonyms |
Carvedilol | Carvedilol Hydrochloride | Dilatrend | Querto | Eucardic | Carvedilol, (S)-isomer | Kredex | BM 14190 | BM-14190 | BM14190 | Carvedilol, (R)-isomer | Carvedilol, (+)-isomer | Carvedilol, (+) | Carvedilol, (+-)-isomer | Carvedilol, (-)-isomer | Carvedilol, (-) | Carvedilol, 14C-labeled | 14C-labeled Carvedilol | Carvedilol, 14C labeled | Coropres | Coreg |
