Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Betaxolol
Drug ID BADD_D00263
Description A cardioselective beta-1-adrenergic antagonist with no partial agonist activity.
Indications and Usage For the management of hypertension.
Marketing Status Prescription; Discontinued
ATC Code C07AB05; S01ED02
DrugBank ID DB00195
KEGG ID D07526
MeSH ID D015784
PubChem ID 2369
TTD Drug ID D03ROX
NDC Product Code 60429-753; 42806-038; 24658-700; 24658-701; 42806-039
Synonyms Betaxolol | Betaxolol Hydrochloride | Hydrochloride, Betaxolol | Kerlone | Oxodal | Kerlon | SL-75212 | SL 75212 | SL75212 | ALO-1401-02 | ALO 1401 02 | ALO140102 | Betoptic | Betoptima | Betaxolol Alcon | Alcon, Betaxolol
Chemical Information
Molecular Formula C18H29NO3
CAS Registry Number 63659-18-7
SMILES CC(C)NCC(COC1=CC=C(C=C1)CCOCC2CC2)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Adverse drug reactionCytochrome P450 2D6P10635T57392Not Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Dysphagia07.01.06.003--
Dyspnoea22.02.01.004; 02.01.03.002--
Dysuria20.02.02.002--
Ear pain04.03.01.003--
Eczema23.03.04.006--
Endophthalmitis11.01.06.003; 06.04.05.009--
Epistaxis24.07.01.005; 22.04.03.001--
Erythema23.03.06.001--Not Available
Erythema of eyelid23.03.06.006; 06.04.04.003--Not Available
Eye discharge06.04.05.001--Not Available
Eye disorder06.08.03.001--Not Available
Eye haemorrhage24.07.05.002; 06.07.02.001--Not Available
Eye irritation06.04.05.003--Not Available
Eye pain06.08.03.002--
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Fibroadenoma of breast21.05.01.005; 16.14.01.001--Not Available
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
Gastrointestinal disorder07.11.01.001--Not Available
Glossitis07.14.01.001--Not Available
Hallucination19.10.02.002--
Headache17.14.01.001--
Heart rate decreased13.14.04.001--Not Available
Hypercholesterolaemia14.08.01.001--Not Available
Hyperglycaemia14.06.02.002; 05.06.02.002--
Hyperhidrosis08.01.03.028; 23.02.03.004--
Hyperkalaemia14.05.03.001--
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
Hyperthyroidism14.11.01.011; 05.02.02.001--
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