Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Atropine
Drug ID BADD_D00189
Description An alkaloid, originally from Atropa belladonna, but found in other plants, mainly solanaceae.
Indications and Usage For the treatment of poisoning by susceptible organophosphorous nerve agents having anti-cholinesterase activity (cholinesterase inhibitors) as well as organophosphorous or carbamate insecticides.
Marketing Status Prescription; Discontinued
ATC Code A03BA01; S01FA01
DrugBank ID DB00572
KEGG ID D00113
MeSH ID D001285
PubChem ID 174174
TTD Drug ID D0RG3O
NDC Product Code 69205-034; 60592-049; 11704-105; 63827-1015; 13371-488; 12714-034; 11704-106; 64181-0048; 11704-107; 11704-101; 11704-104
Synonyms Atropine | Atropinol | Atropine Sulfate | Sulfate, Atropine | Atropine Sulfate Anhydrous | Anhydrous, Atropine Sulfate | Sulfate Anhydrous, Atropine | AtroPen | Atropin Augenöl | Augenöl, Atropin
Chemical Information
Molecular Formula C17H23NO3
CAS Registry Number 51-55-8
SMILES CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Atrial fibrillationNot AvailableF1PE02Not Available25748673
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Enuresis20.02.02.003; 19.07.04.001--Not Available
Erythema23.03.06.0010.002060%Not Available
Extensor plantar response17.02.01.005--Not Available
Extrasystoles02.03.02.003--Not Available
Eye pain06.08.03.002--
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Feeling hot08.01.09.009--Not Available
Flushing24.03.01.002; 23.06.05.003; 08.01.03.0250.001373%
Gastrooesophageal reflux disease07.02.02.003--
Gastrointestinal pain07.01.05.005--
Haemoglobin decreased13.01.05.003--Not Available
Haemoglobin increased13.01.05.004--
Hallucination19.10.02.002--
Hallucination, visual19.10.02.0040.000687%Not Available
Headache17.14.01.0010.001030%
Heart rate increased13.14.04.0020.000687%Not Available
Heterophoria17.02.05.017; 06.05.02.001--Not Available
Hyperglycaemia14.06.02.002; 05.06.02.002--
Hyperhidrosis23.02.03.004; 08.01.03.0280.000687%
Hyperkinesia17.01.02.008--Not Available
Hyperpyrexia08.05.02.002--Not Available
Hyperreflexia17.02.01.002--Not Available
Hypersensitivity10.01.03.003--
Hypertension24.08.02.0010.000687%
Hyperthermia12.05.01.002; 08.05.01.0010.001030%Not Available
Hypertonia17.05.02.001; 15.05.04.0070.000687%Not Available
Hypoglycaemia14.06.03.001; 05.06.03.001--
Hypohidrosis23.02.03.005; 08.01.03.029--
Hypokalaemia14.05.03.002--
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